end-stage renal failure
Persistent expression of Pax2 did not interfere with the initial differentiation of podocytes, but mice ectopically expressing PAX2 developed end-stage renal failure soon after birth.
Persistent expression of <span class="gene" id="16631587-4-25-29">Pax2</span> did not interfere with the initial differentiation of podocytes, but mice ectopically expressing <span class="gene" id="16631587-4-127-131">PAX2</span> developed <span class="disease" id="16631587-4-142-165">end-stage renal failure</span> soon after birth.