medulloblastoma
Assessed against these normal tissue-specific methylation states, S100A6 and S100A10 demonstrated tumour-specific hypermethylation in medulloblastoma primary tumours (5 out of 40 and 4 out of 35, respectively, both 12%) and cell lines (both 7 out of 9, 78%), which was associated with their transcriptional silencing.
Assessed against these normal tissue-specific methylation states, S100A6 and <span class="gene" id="17579622-6-77-84">S100A10</span> demonstrated tumour-specific hypermethylation in <span class="disease" id="17579622-6-134-149">medulloblastoma</span> primary tumours (5 out of 40 and 4 out of 35, respectively, both 12%) and cell lines (both 7 out of 9, 78%), which was associated with their transcriptional silencing.