depression
The association between the IL-6 polymorphism and reduced risk of depressive symptoms confirms the role of the inflammatory response system in the pathophysiology of IFN-alpha-induced depression; in contrast, the effect of the 5-HTT gene was small and perhaps dependent on the status of the inflammatory response.
The association between the IL-6 polymorphism and reduced risk of depressive symptoms confirms the role of the inflammatory response system in the pathophysiology of IFN-alpha-induced <span class="disease" id="18458677-12-184-194">depression</span>; in contrast, the effect of the <span class="gene" id="18458677-12-227-232">5-HTT</span> gene was small and perhaps dependent on the status of the inflammatory response.