breast tumors
The genes identified include eight that are essential for cell proliferation (FGD5, METTL6, CPT1A, DTX3, MRPS23, EIF2S2, EIF6 and SLC2A10) and are uniquely amplified in patients with highly proliferative luminal breast tumors, a clinical subset of patients for which few therapeutic options are effective.
The genes identified include eight that are essential for cell proliferation (FGD5, METTL6, CPT1A, DTX3, MRPS23, EIF2S2, EIF6 and <span class="gene" id="25151356-4-130-137">SLC2A10</span>) and are uniquely amplified in patients with highly proliferative luminal <span class="disease" id="25151356-4-212-225">breast tumors</span>, a clinical subset of patients for which few therapeutic options are effective.