Down syndrome
The 677-1298 T-C haplotype at the MTHFR locus was also a risk factor for Down syndrome (P = 0.0022).
The 677-1298 T-C haplotype at the <span class="gene" id="16845273-7-34-39">MTHFR</span> locus was also a risk factor for <span class="disease" id="16845273-7-73-86">Down syndrome</span> (P = 0.0022).