CF
We conclude that intestinal CFI-3 cells retain the CF phenotype relating to defective regulation of Cl- channels, and therefore constitute a suitable model, 1) for elucidating the function of CFTR protein, 2) developing new therapeutic agents, and 3) correcting the CF defect by gene replacement therapy in vitro.
We conclude that intestinal CFI-3 cells retain the <span class="disease" id="1718974-11-51-53">CF</span> phenotype relating to defective regulation of Cl- channels, and therefore constitute a suitable model, 1) for elucidating the function of <span class="gene" id="1718974-11-192-196">CFTR</span> protein, 2) developing new therapeutic agents, and 3) correcting the <span class="disease" id="1718974-11-266-268">CF</span> defect by gene replacement therapy in vitro.