iron deficiency anemia refractory
Here, we show that iron deficiency anemia refractory to oral iron therapy can be caused by germline mutations in TMPRSS6, which encodes a type II transmembrane serine protease produced by the liver that regulates the expression of the systemic iron regulatory hormone hepcidin.
Here, we show that <span class="disease" id="18408718-2-19-52">iron deficiency anemia refractory</span> to oral iron therapy can be caused by germline mutations in <span class="gene" id="18408718-2-113-120">TMPRSS6</span>, which encodes a type II transmembrane serine protease produced by the liver that regulates the expression of the systemic iron regulatory hormone hepcidin.