PMD
The prototype of primary HMLs is the X-linked Pelizaeus-Merzbacher disease (PMD) caused by mutations in PLP1.
The prototype of primary HMLs is the X-linked <span class="disease" id="18571143-2-46-74">Pelizaeus-Merzbacher disease</span> (<span class="disease" id="18571143-2-76-79">PMD</span>) caused by mutations in <span class="gene" id="18571143-2-104-108">PLP1</span>.