AT
In contrast, in AT cells in which ATM is absent or mutated activation of P53 and its target genes is abrogated, allowing cells to replicate with damage in the presence of As, with cell death ensuing by a pathway different from P53.
In contrast, in <span class="disease" id="11507245-10-16-18">AT</span> cells in which <span class="gene" id="11507245-10-34-37">ATM</span> is absent or mutated activation of P53 and its target genes is abrogated, allowing cells to replicate with damage in the presence of As, with cell death ensuing by a pathway different from P53.