lung tumors
In (A/J x C57BL/6J)F1 mouse lung tumors, the Lmna-rs1 gene was completely downregulated, whereas allele-specific downregulation of the C57BL/6J-derived allele was observed at the Las1 gene, suggesting the potential role of these genes in tumor suppression.
In (A/J x C57BL/6J)F1 mouse <span class="disease" id="15064703-5-28-39">lung tumors</span>, the Lmna-rs1 gene was completely downregulated, whereas allele-specific downregulation of the C57BL/6J-derived allele was observed at the <span class="gene" id="15064703-5-179-183">Las1</span> gene, suggesting the potential role of these genes in tumor suppression.