POF
The coding region of WT1 gene was screened in 384 patients with POF and 6 novel variations were identified, including two missense mutations (p. Pro126Ser in exon1 and p. Arg370His in exon7) and four intronic variants (c.647-27C?>?T, c.647-13G?>?C, c.647-13G?>?A in intron1 and c.950?+?14T?>?C in intron 4).
The coding region of <span class="gene" id="26358501-4-21-24">WT1</span> gene was screened in 384 patients with <span class="disease" id="26358501-4-64-67">POF</span> and 6 novel variations were identified, including two missense mutations (p. Pro126Ser in exon1 and p. Arg370His in exon7) and four intronic variants (c.647-27C?&gt;?T, c.647-13G?&gt;?C, c.647-13G?&gt;?A in intron1 and c.950?+?14T?&gt;?C in intron 4).