hepatocellular carcinomas
Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes.
Highly metastatic <span class="disease" id="9029167-0-18-43">hepatocellular carcinomas</span> induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of <span class="gene" id="9029167-0-172-175">p53</span> gene mutations along with altered mRNA expression of tumor-related genes.