cleft palate
We find that, similar to the way in which SATB2 is perceived to act in humans, craniofacial defects due to haploinsufficiency of Satb2, including cleft palate (in approximately 25% of cases), phenocopy those seen with 2q32-q33 deletions and translocations in humans.
We find that, similar to the way in which <span class="gene" id="16960803-2-42-47">SATB2</span> is perceived to act in humans, craniofacial defects due to haploinsufficiency of <span class="gene" id="16960803-2-129-134">Satb2</span>, including <span class="disease" id="16960803-2-146-158">cleft palate</span> (in approximately 25% of cases), phenocopy those seen with 2q32-q33 deletions and translocations in humans.