dengue haemorrhagic fever
Our observation that blockade of CLEC5A-mediated signalling attenuates the production of proinflammatory cytokines by macrophages infected with DV (either alone or complexed with an enhancing antibody) offers a promising strategy for alleviating tissue damage and increasing the survival of patients suffering from dengue haemorrhagic fever and dengue shock syndrome, and possibly even other virus-induced inflammatory diseases.
Our observation that blockade of <span class="gene" id="18496526-7-33-39">CLEC5A</span>-mediated signalling attenuates the production of proinflammatory cytokines by macrophages infected with DV (either alone or complexed with an enhancing antibody) offers a promising strategy for alleviating tissue damage and increasing the survival of patients suffering from <span class="disease" id="18496526-7-315-340">dengue haemorrhagic fever</span> and dengue shock syndrome, and possibly even other virus-induced inflammatory diseases.