atherosclerosis
In contrast to human plaques, levels of 5-LO mRNA are not significantly increased in plaque tissues from two atherosclerosis-prone mouse strains, and mouse plaques exhibit segregated cellular expression of LTA4H and 5-LO as well as strong increases of CysLT1 and CysLT2 mRNA.
In contrast to human plaques, levels of <span class="gene" id="16698924-7-40-44">5-LO</span> mRNA are not significantly increased in plaque tissues from two <span class="disease" id="16698924-7-109-124">atherosclerosis</span>-prone mouse strains, and mouse plaques exhibit segregated cellular expression of LTA4H and <span class="gene" id="16698924-7-216-220">5-LO</span> as well as strong increases of CysLT1 and CysLT2 mRNA.