uremia
During the course of nephrotic syndrome, serum urea concentrations increased significantly faster in sgk1(-/-) mice than in sgk1(+/+) mice leading to uremia and a reduced median survival in sgk1(-/-) mice (29 vs. 40 days in sgk1(+/+) mice).
During the course of nephrotic syndrome, serum urea concentrations increased significantly faster in <span class="gene" id="18768591-8-101-105">sgk1</span>(-/-) mice than in <span class="gene" id="18768591-8-124-128">sgk1</span>(+/+) mice leading to <span class="disease" id="18768591-8-150-156">uremia</span> and a reduced median survival in <span class="gene" id="18768591-8-190-194">sgk1</span>(-/-) mice (29 vs. 40 days in <span class="gene" id="18768591-8-224-228">sgk1</span>(+/+) mice).