obesity
The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene encoding leptin, an adipocyte-specific secreted protein which has profound effects on appetite and energy expenditure.
The extreme <span class="disease" id="9202122-1-12-19">obesity</span> of the obese (ob/ob) mouse is attributable to mutations in the gene encoding <span class="gene" id="9202122-1-97-103">leptin</span>, an adipocyte-specific secreted protein which has profound effects on appetite and energy expenditure.