A?
Importantly, we found that Trien blocked the receptor for AGEs (RAGE), downregulated ?-site APP cleaving enzyme 1 (BACE1), inhibited amyloidogenic APP cleavage, and subsequently reduced A? levels.
Importantly, we found that Trien blocked the receptor for AGEs (RAGE), downregulated &beta;-site APP cleaving enzyme 1 (BACE1), inhibited amyloidogenic <span class="gene" id="23541064-5-147-150">APP</span> cleavage, and subsequently reduced <span class="disease" id="23541064-5-186-188">A&beta;</span> levels.