leukemia
Here, we report on the synthesis of TMPP and DMPP and demonstrate that these agents hinder proliferation of leukemia cells by FoxM1 suppression, which leads to G2/M cell cycle block and subsequent caspase-3-dependent apoptosis in acute leukemia cells.
Here, we report on the synthesis of TMPP and DMPP and demonstrate that these agents hinder proliferation of <span class="disease" id="19436953-7-108-116">leukemia</span> cells by <span class="gene" id="19436953-7-126-131">FoxM1</span> suppression, which leads to G2/M cell cycle block and subsequent caspase-3-dependent apoptosis in acute leukemia cells.