tumorigenesis
Here we show decreasing the levels of CTR1 (Cu transporter 1), or mutations in MEK1 that disrupt Cu binding, decreased BRAF(V600E)-driven signalling and tumorigenesis in mice and human cell settings.
Here we show decreasing the levels of CTR1 (Cu transporter 1), or mutations in MEK1 that disrupt Cu binding, decreased <span class="gene" id="24717435-5-119-123">BRAF</span>(V600E)-driven signalling and <span class="disease" id="24717435-5-153-166">tumorigenesis</span> in mice and human cell settings.