myeloproliferative neoplasm
The 8p11 myeloproliferative syndrome is a rare, aggressive myeloproliferative neoplasm characterized by constitutively active FGFR1 fusion proteins that arise from specific chromosomal translocations and which drive aberrant proliferation.
The 8p11 myeloproliferative syndrome is a rare, aggressive <span class="disease" id="22875613-1-59-86">myeloproliferative neoplasm</span> characterized by constitutively active <span class="gene" id="22875613-1-126-131">FGFR1</span> fusion proteins that arise from specific chromosomal translocations and which drive aberrant proliferation.