uveal melanoma
We analyzed genomics data from 136 uveal melanoma samples and found a recurrent mutation in CYSLTR2 (cysteinyl leukotriene receptor 2) encoding a p.Leu129Gln substitution in 4 of 9 samples that lacked mutations in GNAQ, GNA11, and PLCB4 but in 0 of 127 samples that harbored mutations in these genes.
We analyzed genomics data from 136 <span class="disease" id="27089179-3-35-49">uveal melanoma</span> samples and found a recurrent mutation in CYSLTR2 (cysteinyl leukotriene receptor 2) encoding a p.Leu129Gln substitution in 4 of 9 samples that lacked mutations in GNAQ, GNA11, and <span class="gene" id="27089179-3-231-236">PLCB4</span> but in 0 of 127 samples that harbored mutations in these genes.