myelofibrosis
We report here that JAK2(V617F)-associated disease is strongly associated with a specific constitutional JAK2 haplotype, designated 46/1, in all three disease entities compared to healthy controls (polycythemia vera, n = 192, P = 2.9 x 10(-16); essential thrombocythemia, n = 78, P = 8.2 x 10(-9) and myelofibrosis, n = 41, P = 8.0 x 10(-5)).
We report here that <span class="gene" id="19287382-3-20-24">JAK2</span>(V617F)-associated disease is strongly associated with a specific constitutional <span class="gene" id="19287382-3-105-109">JAK2</span> haplotype, designated 46/1, in all three disease entities compared to healthy controls (polycythemia vera, n = 192, P = 2.9 x 10(-16); essential thrombocythemia, n = 78, P = 8.2 x 10(-9) and <span class="disease" id="19287382-3-301-314">myelofibrosis</span>, n = 41, P = 8.0 x 10(-5)).