polydactyly
Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacial area, the formation of split sternum and the development of polydactyly.
Here we demonstrate that conditional inactivation of the <span class="gene" id="17698054-2-57-62">Kif3a</span> subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacial area, the formation of split sternum and the development of <span class="disease" id="17698054-2-277-288">polydactyly</span>.