mental retardation
The leucine zipper-, EF-hand-containing transmembrane protein 1 (LETM1) has recently been cloned in an attempt to identify genes deleted in Wolf-Hirschhorn syndrome (WHS), a microdeletion syndrome characterized by severe growth and mental retardation, hypotonia, seizures, and typical facial dysmorphic features.
The <span class="gene" id="14706454-1-4-63">leucine zipper-, EF-hand-containing transmembrane protein 1</span> (<span class="gene" id="14706454-1-65-70">LETM1</span>) has recently been cloned in an attempt to identify genes deleted in Wolf-Hirschhorn syndrome (WHS), a microdeletion syndrome characterized by severe growth and <span class="disease" id="14706454-1-232-250">mental retardation</span>, hypotonia, seizures, and typical facial dysmorphic features.