polydactyly
Limb polydactyly in talpid(3) suggests a gain of Hedgehog (Hh) signaling, whereas, paradoxically, absence of midline facial structures suggests a loss of Hh function.
Limb <span class="disease" id="15554946-2-5-16">polydactyly</span> in <span class="gene" id="15554946-2-20-28">talpid(3</span>) suggests a gain of Hedgehog (Hh) signaling, whereas, paradoxically, absence of midline facial structures suggests a loss of Hh function.