optic atrophy
Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy.
Mutations in <span class="gene" id="22842229-0-13-19">NMNAT1</span> cause Leber congenital amaurosis with early-onset severe macular and <span class="disease" id="22842229-0-89-102">optic atrophy</span>.