HD
As opposed to the effect of depleting wild-type huntingtin, specifically silencing the mutant species actually lowered caspase-3 activation and protected HD cells under stress conditions.
As opposed to the effect of depleting wild-type <span class="gene" id="19094060-10-48-58">huntingtin</span>, specifically silencing the mutant species actually lowered caspase-3 activation and protected <span class="disease" id="19094060-10-154-156">HD</span> cells under stress conditions.