obesity
Training reduced 4-HNE (-10%; P?0.04), PC (-21%; P?0.05), 8-isoprostane (-26%; P?0.02) and leptin levels (-33%; P?0.01); had a tendency to decrease IL-6 levels (-21%; P=0.07) and IR (-17%; P=0.10); and increased manganese SOD (MnSOD) levels (+47%; P?0.01).Conclusion:Endurance exercise reduced skeletal muscle-specific and systemic oxidative damage while improving IR and cytokine profile associated with obesity, independent of weight loss.
Training reduced 4-HNE (-10%; P?0.04), PC (-21%; P?0.05), 8-isoprostane (-26%; P?0.02) and <span class="gene" id="24042701-5-91-97">leptin</span> levels (-33%; P?0.01); had a tendency to decrease IL-6 levels (-21%; P=0.07) and IR (-17%; P=0.10); and increased manganese SOD (MnSOD) levels (+47%; P?0.01).Conclusion:Endurance exercise reduced skeletal muscle-specific and systemic oxidative damage while improving IR and cytokine profile associated with <span class="disease" id="24042701-5-405-412">obesity</span>, independent of weight loss.