myelofibrosis
Screening of a total of 614 individuals with myeloid disorders revealed 49 monoallelic or biallelic EZH2 mutations in 42 individuals; the mutations were found most commonly in those with myelodysplastic/myeloproliferative neoplasms (27 out of 219 individuals, or 12%) and in those with myelofibrosis (4 out of 30 individuals, or 13%).
Screening of a total of 614 individuals with myeloid disorders revealed 49 monoallelic or biallelic <span class="gene" id="20601953-3-100-104">EZH2</span> mutations in 42 individuals; the mutations were found most commonly in those with myelodysplastic/myeloproliferative neoplasms (27 out of 219 individuals, or 12%) and in those with <span class="disease" id="20601953-3-286-299">myelofibrosis</span> (4 out of 30 individuals, or 13%).