Leber congenital amaurosis
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital amaurosis (LCA), a severe visual impairment in humans.
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (<span class="gene" id="19339306-1-94-98">LRAT</span>) genes cause <span class="disease" id="19339306-1-112-138">Leber congenital amaurosis</span> (LCA), a severe visual impairment in humans.