DLBCL
These results demonstrate a critical function of PI3K-PDK1 signaling upstream of MALT1 protease and NF-?B in distinct ABC DLBCL cells and provide a rationale for the pharmacologic use of PI3K inhibitors in DLBCL therapy.
These results demonstrate a critical function of <span class="gene" id="21173233-6-49-53">PI3K</span>-PDK1 signaling upstream of MALT1 protease and NF-&kappa;B in distinct ABC DLBCL cells and provide a rationale for the pharmacologic use of <span class="gene" id="21173233-6-187-191">PI3K</span> inhibitors in <span class="disease" id="21173233-6-206-211">DLBCL</span> therapy.