anxiety
Using mice heterozygous for peptidylglycine alpha-amidating monooxygenase (PAM), a cuproenzyme essential for the synthesis of many neuropeptides, we identified alterations in anxiety-like behavior, thermoregulation and seizure sensitivity.
Using mice heterozygous for <span class="gene" id="19815072-4-28-73">peptidylglycine alpha-amidating monooxygenase</span> (<span class="gene" id="19815072-4-75-78">PAM</span>), a cuproenzyme essential for the synthesis of many neuropeptides, we identified alterations in <span class="disease" id="19815072-4-175-182">anxiety</span>-like behavior, thermoregulation and seizure sensitivity.