AML
We identified such mutations using a Sleeping Beauty transposon, which caused rapid-onset AML in 80% of mice with Npm1c, associated with mutually exclusive integrations in Csf2, Flt3 or Rasgrp1 in 55 of 70 leukemias.
We identified such mutations using a Sleeping Beauty transposon, which caused rapid-onset <span class="disease" id="21441929-5-90-93">AML</span> in 80% of mice with Npm1c, associated with mutually exclusive integrations in Csf2, Flt3 or <span class="gene" id="21441929-5-186-193">Rasgrp1</span> in 55 of 70 leukemias.