conductive hearing loss
Eya1 heterozygotes show renal abnormalities and a conductive hearing loss similar to BOR syndrome, whereas Eya1 homozygotes lack ears and kidneys due to defective inductive tissue interactions and apoptotic regression of the organ primordia.
<span class="gene" id="10471511-3-0-4">Eya1</span> heterozygotes show renal abnormalities and a <span class="disease" id="10471511-3-50-73">conductive hearing loss</span> similar to BOR syndrome, whereas <span class="gene" id="10471511-3-107-111">Eya1</span> homozygotes lack ears and kidneys due to defective inductive tissue interactions and apoptotic regression of the organ primordia.