ALS
A predilection for disease onset in the lower limbs appears to be a distinguishing feature of familial ALS with SOD-1 mutations, and accords with findings in transgenic mouse models.
A predilection for disease onset in the lower limbs appears to be a distinguishing feature of familial <span class="disease" id="9065559-6-103-106">ALS</span> with <span class="gene" id="9065559-6-112-117">SOD-1</span> mutations, and accords with findings in transgenic mouse models.