osteosarcoma
Cytotoxicity assays showed that the resistance of the osteosarcoma cell lines to etoposide correlated with PXR protein expression levels and activation of P450 3A4 and could be prevented by ketoconazole.
Cytotoxicity assays showed that the resistance of the <span class="disease" id="17279585-8-54-66">osteosarcoma</span> cell lines to etoposide correlated with <span class="gene" id="17279585-8-107-110">PXR</span> protein expression levels and activation of P450 3A4 and could be prevented by ketoconazole.