HCC
Molecular biological analyses of the induced lesions revealed point mutations in the p53 gene in 60.9% of HCCs, and elevated expression of mRNAs for p53, c-myc, c-fos, TGF-alpha, TGF-beta1, alpha-fetoprotein, GST-P, and GGT, and decreased mRNA expression of EGF and EGFR in HCCs when compared to controls.
Molecular biological analyses of the induced lesions revealed point mutations in the p53 gene in 60.9% of <span class="disease" id="9029167-4-106-109">HCC</span>s, and elevated expression of mRNAs for p53, c-myc, c-fos, TGF-alpha, TGF-beta1, <span class="gene" id="9029167-4-190-207">alpha-fetoprotein</span>, GST-P, and GGT, and decreased mRNA expression of EGF and EGFR in <span class="disease" id="9029167-4-274-277">HCC</span>s when compared to controls.