ovarian tumors
Investigation of primary tumors revealed that the Sparc promoter is methylated in 68% of primary ovarian tumors and that the levels of SPARC protein decrease as the disease progresses from low to high grade.
Investigation of primary tumors revealed that the <span class="gene" id="19177197-8-50-55">Sparc</span> promoter is methylated in 68% of primary <span class="disease" id="19177197-8-97-111">ovarian tumors</span> and that the levels of <span class="gene" id="19177197-8-135-140">SPARC</span> protein decrease as the disease progresses from low to high grade.