HNSCC
Although consistent inhibition of the PI3K pathway was not evident in HNSCC, we identified a combination of PI3K/TP53 events necessary, but not sufficient, for rigosertib sensitivity.
Although consistent inhibition of the <span class="gene" id="23873848-10-38-42">PI3K</span> pathway was not evident in <span class="disease" id="23873848-10-70-75">HNSCC</span>, we identified a combination of <span class="gene" id="23873848-10-108-112">PI3K</span>/TP53 events necessary, but not sufficient, for rigosertib sensitivity.