AD
The strikingly reduced CNS expression of genes encoding insulin, IGF-I, and IGF-II, as well as the insulin and IGF-I receptors, suggests that AD may represent a neuro-endocrine disorder that resembles, yet is distinct from diabetes mellitus.
The strikingly reduced CNS expression of genes encoding insulin, <span class="gene" id="15750215-6-65-70">IGF-I</span>, and IGF-II, as well as the insulin and <span class="gene" id="15750215-6-111-116">IGF-I</span> receptors, suggests that <span class="disease" id="15750215-6-142-144">AD</span> may represent a neuro-endocrine disorder that resembles, yet is distinct from diabetes mellitus.