inflammatory bowel disease
In inflammatory bowel disease, increased production of prostaglandins by cyclooxygenase-2 (COX-2) contributes to bowel dysfunction, inflammatory edema, and hyperemia suggesting that inhibitors of COX-2 may have beneficial effect in gut inflammation.
In <span class="disease" id="11820457-1-3-29">inflammatory bowel disease</span>, increased production of prostaglandins by <span class="gene" id="11820457-1-73-89">cyclooxygenase-2</span> (<span class="gene" id="11820457-1-91-96">COX-2</span>) contributes to bowel dysfunction, inflammatory edema, and hyperemia suggesting that inhibitors of <span class="gene" id="11820457-1-196-201">COX-2</span> may have beneficial effect in gut inflammation.