autoimmune condition
Treatment with gold in the form of aurothiomaleate, silver or mercury (Hg) in genetically susceptible mouse strains (H-2(s)) induces a systemic autoimmune condition characterized by anti-nuclear antibodies targeting the 34-kDa nucleolar protein fibrillarin, as well as lymphoproliferation and systemic immune-complex (IC) deposits.
Treatment with gold in the form of aurothiomaleate, silver or mercury (Hg) in genetically susceptible mouse strains (H-2(s)) induces a systemic <span class="disease" id="19077085-1-144-164">autoimmune condition</span> characterized by anti-nuclear antibodies targeting the 34-kDa nucleolar protein <span class="gene" id="19077085-1-245-256">fibrillarin</span>, as well as lymphoproliferation and systemic immune-complex (IC) deposits.