FXS
Subjects with FXS and fragile X mental retardation gene knock out (Fmr1 KO) mice, an animal model for FXS, have been shown to exhibit defects in dendritic spine maturation that may underlie cognitive and behavioural abnormalities in FXS.
Subjects with <span class="disease" id="18835858-2-14-17">FXS</span> and fragile X mental retardation gene knock out (<span class="gene" id="18835858-2-67-71">Fmr1</span> KO) mice, an animal model for <span class="disease" id="18835858-2-102-105">FXS</span>, have been shown to exhibit defects in dendritic spine maturation that may underlie cognitive and behavioural abnormalities in <span class="disease" id="18835858-2-233-236">FXS</span>.