PCD
Here, we identify the DRC1 subunit of the nexin-dynein regulatory complex (N-DRC), an axonemal structure critical for the regulation of dynein motors, and show that mutations in the gene encoding DRC1, CCDC164, are involved in PCD pathogenesis.
Here, we identify the <span class="gene" id="23354437-2-22-26">DRC1</span> subunit of the nexin-dynein regulatory complex (N-DRC), an axonemal structure critical for the regulation of dynein motors, and show that mutations in the gene encoding <span class="gene" id="23354437-2-196-200">DRC1</span>, <span class="gene" id="23354437-2-202-209">CCDC164</span>, are involved in <span class="disease" id="23354437-2-227-230">PCD</span> pathogenesis.