bipolar disorder
Thus, the present observations suggest that dysregulation of intracellular signaling mediated by PDE4B is a significant factor in the cause and expression, respectively, of schizophrenia and bipolar disorder and that targeting PDE4B-regulated signaling pathways may yield new therapies to treat the totality of these disorders.
Thus, the present observations suggest that dysregulation of intracellular signaling mediated by <span class="gene" id="18394866-6-97-102">PDE4B</span> is a significant factor in the cause and expression, respectively, of schizophrenia and <span class="disease" id="18394866-6-191-207">bipolar disorder</span> and that targeting <span class="gene" id="18394866-6-227-232">PDE4B</span>-regulated signaling pathways may yield new therapies to treat the totality of these disorders.