hepatic steatosis
In defining the functional relevance of STS induction in metabolic disease, we showed that overexpression of STS in the liver of transgenic mice alleviated HFD and ob/ob models of obesity and type 2 diabetes, including reduced body weight, improved insulin sensitivity, and decreased hepatic steatosis and inflammation.
In defining the functional relevance of <span class="gene" id="24497646-3-40-43">STS</span> induction in metabolic disease, we showed that overexpression of <span class="gene" id="24497646-3-109-112">STS</span> in the liver of transgenic mice alleviated HFD and ob/ob models of obesity and type 2 diabetes, including reduced body weight, improved insulin sensitivity, and decreased <span class="disease" id="24497646-3-284-301">hepatic steatosis</span> and inflammation.