hypertension
The findings indicated that the expression of PTEN is reduced in hypertensive aorta, that the reduced PTEN experession can be reversed by captopril treatment, that AngII and the increased mechanical strain may participate in regulating expression of PTEN, and that PTEN may play a role in the arterial remodeling induced by hypertension.
The findings indicated that the expression of <span class="gene" id="15646324-9-46-50">PTEN</span> is reduced in hypertensive aorta, that the reduced <span class="gene" id="15646324-9-102-106">PTEN</span> experession can be reversed by captopril treatment, that AngII and the increased mechanical strain may participate in regulating expression of <span class="gene" id="15646324-9-250-254">PTEN</span>, and that <span class="gene" id="15646324-9-265-269">PTEN</span> may play a role in the arterial remodeling induced by <span class="disease" id="15646324-9-324-336">hypertension</span>.