Dent's disease
Thus, mutations that result in a loss of function of the voltage-gated chloride channel, CLC-5, are associated with Dent's disease, which is characterized by low-molecular weight proteinuria, hypercalciuria, nephrolithiasis, and renal failure.
Thus, mutations that result in a loss of function of the voltage-gated chloride channel, <span class="gene" id="10561751-2-89-94">CLC-5</span>, are associated with <span class="disease" id="10561751-2-116-130">Dent's disease</span>, which is characterized by low-molecular weight proteinuria, hypercalciuria, nephrolithiasis, and renal failure.