leiomyomas
Taken together, these results suggest that downregulation of activin A and Smad3, both members of the TGF-? pathway, may offer a mechanistic explanation for the inhibitory effect of a high-dose of genistein on UtLM cells, and might be potential therapeutic targets for treatment of clinical cases of uterine leiomyomas.
Taken together, these results suggest that downregulation of activin A and <span class="gene" id="22228119-6-75-80">Smad3</span>, both members of the TGF-&beta; pathway, may offer a mechanistic explanation for the inhibitory effect of a high-dose of genistein on UtLM cells, and might be potential therapeutic targets for treatment of clinical cases of uterine <span class="disease" id="22228119-6-308-318">leiomyomas</span>.