thrombocytopenia
These findings indicate that antibodies associated with HITP react with PF4 complexed with heparin in solution or with glycosaminoglycan molecules on the surface of endothelial cells and provide the basis for a new hypothesis to explain the development of thrombocytopenia with thrombosis or disseminated intravascular coagulation in patients sensitive to heparin.
These findings indicate that antibodies associated with HITP react with <span class="gene" id="8282825-8-72-75">PF4</span> complexed with heparin in solution or with glycosaminoglycan molecules on the surface of endothelial cells and provide the basis for a new hypothesis to explain the development of <span class="disease" id="8282825-8-256-272">thrombocytopenia</span> with thrombosis or disseminated intravascular coagulation in patients sensitive to heparin.