AD
Our data strongly support a major role of PPARgamma in the modulation of amyloid-beta generation by inflammation and suggest that the protective mechanism of NSAIDs in AD involves activation of PPARgamma and decreased BACE1 gene transcription.
Our data strongly support a major role of PPARgamma in the modulation of amyloid-beta generation by inflammation and suggest that the protective mechanism of NSAIDs in <span class="disease" id="16407166-11-168-170">AD</span> involves activation of PPARgamma and decreased <span class="gene" id="16407166-11-218-223">BACE1</span> gene transcription.