metastasis
A marked decrease on EGFR phosphorylation (P < 0.01) and c-Myc activation (P = 0.02) was observed in patients with R497K polymorphism, which is associated with decreased invasion (P = 0.01), lower nodal involvement (P = 0.02), reduced subsequent metastasis (P < 0.01), and longer disease-free (P < 0.01) as well as overall (P < 0.01) survival in stage II/III colorectal carcinoma patients who had received curative surgery.
A marked decrease on <span class="gene" id="17575224-5-21-25">EGFR</span> phosphorylation (P &lt; 0.01) and c-Myc activation (P = 0.02) was observed in patients with R497K polymorphism, which is associated with decreased invasion (P = 0.01), lower nodal involvement (P = 0.02), reduced subsequent <span class="disease" id="17575224-5-246-256">metastasis</span> (P &lt; 0.01), and longer disease-free (P &lt; 0.01) as well as overall (P &lt; 0.01) survival in stage II/III colorectal carcinoma patients who had received curative surgery.