ESCC
We confirmed the known association of the ALDH2 locus on 12q24 to ESCC, and a joint analysis showed that drinkers with both of the ADH1B and ALDH2 risk alleles had a fourfold increased risk for ESCC compared to drinkers without these risk alleles.
We confirmed the known association of the ALDH2 locus on 12q24 to <span class="disease" id="22960999-4-66-70">ESCC</span>, and a joint analysis showed that drinkers with both of the <span class="gene" id="22960999-4-131-136">ADH1B</span> and ALDH2 risk alleles had a fourfold increased risk for <span class="disease" id="22960999-4-194-198">ESCC</span> compared to drinkers without these risk alleles.