Nephrotic syndrome
Nephrotic syndrome induced by puromycin aminonucleoside (PAN) is characterized by tubulointerstitial (TI) inflammation, foci of TI fibrosis, and increased renal mRNA levels for matrix genes, the tissue inhibitor of metalloproteinases (TIMP), and the transforming growth factor-beta 1 (TGF-beta 1).
<span class="disease" id="8023968-1-0-18">Nephrotic syndrome</span> induced by puromycin aminonucleoside (PAN) is characterized by tubulointerstitial (TI) inflammation, foci of TI fibrosis, and increased renal mRNA levels for matrix genes, the tissue inhibitor of metalloproteinases (TIMP), and the <span class="gene" id="8023968-1-250-283">transforming growth factor-beta 1</span> (<span class="gene" id="8023968-1-285-295">TGF-beta 1</span>).