obesity
Evidence was based on the observation that knock-out mice for the HTR2C receptor gene develop obesity and that many antipsychotics (AP) with potent HTR2C antagonism may induce weight gain in susceptible individuals.
Evidence was based on the observation that knock-out mice for the <span class="gene" id="17702092-2-66-71">HTR2C</span> receptor gene develop <span class="disease" id="17702092-2-94-101">obesity</span> and that many antipsychotics (AP) with potent <span class="gene" id="17702092-2-148-153">HTR2C</span> antagonism may induce weight gain in susceptible individuals.