thymic stromal lymphopoietin
We previously reported that selective ablation of the nuclear receptors retinoid X receptor (RXR)-a and RXR-b in mouse epidermal keratinocytes (RXR-ab<sup>ep-/-</sup>) or a topical application of active vitamin D3 (VD3) and/or all-trans retinoic acid (RA) on wild-type mouse skin induces a human atopic dermatitis-like phenotype that is triggered by an increased expression of the thymic stromal lymphopoietin (TSLP) proinflammatory cytokine.