gliomas
To understand the molecular mechanisms underlying the malignant progression of low-grade gliomas with mutations in IDH1 (encoding isocitrate dehydrogenase 1), we studied paired tumor samples from 41 patients, comparing higher-grade, progressed samples to their lower-grade counterparts.
To understand the molecular mechanisms underlying the malignant progression of low-grade <span class="disease" id="26618343-2-89-96">gliomas</span> with mutations in <span class="gene" id="26618343-2-115-119">IDH1</span> (encoding isocitrate dehydrogenase 1), we studied paired tumor samples from 41 patients, comparing higher-grade, progressed samples to their lower-grade counterparts.