hypopigmentation
Complementation tests using a second allele of Gli3 (Gli3(Xt-J)) confirmed that a null mutation of Gli3 causes the increased hypopigmentation in Sox10(LacZ/+);Gli3(Mos1/)(+) double heterozygotes.
Complementation tests using a second allele of <span class="gene" id="18397875-6-47-51">Gli3</span> (<span class="gene" id="18397875-6-53-63">Gli3(Xt-J)</span>) confirmed that a null mutation of <span class="gene" id="18397875-6-99-103">Gli3</span> causes the increased <span class="disease" id="18397875-6-125-141">hypopigmentation</span> in Sox10(LacZ/+);<span class="gene" id="18397875-6-159-163">Gli3</span>(Mos1/)(+) double heterozygotes.