EPP
Erythropoietic protoporphyria (EPP) is an inherited disease characterised by a ferrochelatase (FECH) deficiency, the latest enzyme of the heme biosynthetic pathway, leading to the accumulation of toxic protoporphyrin in the liver, bone marrow and spleen.
<span class="disease" id="12950064-1-0-29">Erythropoietic protoporphyria</span> (<span class="disease" id="12950064-1-31-34">EPP</span>) is an inherited disease characterised by a <span class="gene" id="12950064-1-79-93">ferrochelatase</span> (<span class="gene" id="12950064-1-95-99">FECH</span>) deficiency, the latest enzyme of the heme biosynthetic pathway, leading to the accumulation of toxic protoporphyrin in the liver, bone marrow and spleen.