SLE
Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).
Aside from the expected strong association between <span class="disease" id="18204446-3-51-54">SLE</span> and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus <span class="gene" id="18204446-3-136-140">IRF5</span> on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) &lt; P(overall) &lt; 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).