HCC
We also identified recurrent HBV integration events (in ? 4 HCCs) that were validated by RNA sequencing (RNA-seq) and Sanger sequencing at the known and putative cancer-related TERT, MLL4 and CCNE1 genes, which showed upregulated gene expression in tumor versus normal tissue.
We also identified recurrent HBV integration events (in &ge; 4 <span class="disease" id="22634754-5-60-63">HCC</span>s) that were validated by RNA sequencing (RNA-seq) and Sanger sequencing at the known and putative cancer-related TERT, <span class="gene" id="22634754-5-183-187">MLL4</span> and CCNE1 genes, which showed upregulated gene expression in tumor versus normal tissue.