megaloblastic anemia
Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease.
Dihydrofolate reductase deficiency due to a homozygous <span class="gene" id="21310277-0-55-59">DHFR</span> mutation causes <span class="disease" id="21310277-0-76-96">megaloblastic anemia</span> and cerebral folate deficiency leading to severe neurologic disease.