multicatalytic endopeptidase complex-like 1
To study the effect of immunoproteasomes on LPS- or TNF-a-induced NF-kB activation, we used IFN-y stimulated peritoneal macrophages and mouse embryonic fibroblasts derived from mice deficient for the immunoproteasome subunits low molecular mass polypeptide (LMP) 2, or LMP7 and multicatalytic endopeptidase complex-like 1 (MECL-1).