ALS
The aim of the work was (1) investigating on gender-dependence of disease progression in the standard model for ALS - the transgenic mouse bearing superoxide dismutase 1 gene mutations - and (2) assessing if a P2X7 receptor antagonist treatment should take into account sexual dimorphism.
The aim of the work was (1) investigating on gender-dependence of disease progression in the standard model for <span class="disease" id="23583883-6-112-115">ALS</span> - the transgenic mouse bearing <span class="gene" id="23583883-6-147-169">superoxide dismutase 1</span> gene mutations - and (2) assessing if a P2X7 receptor antagonist treatment should take into account sexual dimorphism.