MFS
The study employed a well-characterized animal model of MFS, namely fibrillin-1 under-expressing mice (mgR/mgR mice) that die spontaneously from rupture of the thoracic aorta between 2 to 4 months of age.
The study employed a well-characterized animal model of <span class="disease" id="18178469-6-56-59">MFS</span>, namely <span class="gene" id="18178469-6-68-79">fibrillin-1</span> under-expressing mice (mgR/mgR mice) that die spontaneously from rupture of the thoracic aorta between 2 to 4 months of age.