breast tumours
In the present study, we found frequent methylation of SFRP family genes in breast cancer cell lines (SFRP1, 7 out of 11, 64%; SFRP2, 11 out of 11, 100%; SFRP5, 10 out of 11, 91%) and primary breast tumours (SFRP1, 31 out of 78, 40%; SFRP2, 60 out of 78, 77%; SFRP5, 55 out of 78, 71%).
In the present study, we found frequent methylation of SFRP family genes in breast cancer cell lines (<span class="gene" id="18283316-3-102-107">SFRP1</span>, 7 out of 11, 64%; SFRP2, 11 out of 11, 100%; SFRP5, 10 out of 11, 91%) and primary <span class="disease" id="18283316-3-192-206">breast tumours</span> (<span class="gene" id="18283316-3-208-213">SFRP1</span>, 31 out of 78, 40%; SFRP2, 60 out of 78, 77%; SFRP5, 55 out of 78, 71%).