intestinal polyps
As with cyclooxygenase (COX)-2, genetic disruption of COX-1 gene or pharmacologic inhibition of its activity has been shown to decrease the number of intestinal polyps in Apc gene-deficient mice.
As with cyclooxygenase (COX)-2, genetic disruption of COX-1 gene or pharmacologic inhibition of its activity has been shown to decrease the number of <span class="disease" id="14991580-1-150-167">intestinal polyps</span> in <span class="gene" id="14991580-1-171-174">Apc</span> gene-deficient mice.