hyper IgE syndrome
These findings emphasize the critical role of STAT3 in autoimmune disease and contrast with the germline inactivating STAT3 mutations that result in hyper IgE syndrome.
These findings emphasize the critical role of <span class="gene" id="25038750-3-46-51">STAT3</span> in autoimmune disease and contrast with the germline inactivating <span class="gene" id="25038750-3-118-123">STAT3</span> mutations that result in <span class="disease" id="25038750-3-149-167">hyper IgE syndrome</span>.