MCL
PIK3IP1, a negative PI3K regulator, appears to mediate pG1 sensitization to PI3K inhibition; it is markedly reduced in MCL tumor cells compared with normal peripheral B cells, profoundly induced in pG1 and required for pG1 sensitization to GS-1101.
PIK3IP1, a negative <span class="gene" id="23676220-8-20-24">PI3K</span> regulator, appears to mediate pG1 sensitization to <span class="gene" id="23676220-8-76-80">PI3K</span> inhibition; it is markedly reduced in <span class="disease" id="23676220-8-119-122">MCL</span> tumor cells compared with normal peripheral B cells, profoundly induced in pG1 and required for pG1 sensitization to GS-1101.