COPD
Theophylline induced a sixfold increase in HDAC activity in COPD AM lysates and significantly enhanced dexamethasone suppression of induced IL-8 release, an effect that was blocked by the HDAC inhibitor trichostatin A.
Theophylline induced a sixfold increase in HDAC activity in <span class="disease" id="15337792-6-60-64">COPD</span> AM lysates and significantly enhanced dexamethasone suppression of induced <span class="gene" id="15337792-6-140-144">IL-8</span> release, an effect that was blocked by the HDAC inhibitor trichostatin A.