na-agafe n'okpuru ma zaa ajụjụ ahụ mgbe e mesịrị n'otu asụsụ ahụ dị ka akụkụ ahụ: Ntughari: Nucleases bụ enzymes nke na-egbutu eriri DNA site na catalyzing hydrolysis nke phosphodiester bonds. A na-akpọ nucleases nke na-egbutu nucleotides site na njedebe nke eriri DNA bụ exonucleases, ebe endonucleases na-egbutu n'ime eriri. A na-akpọkarị nucleases ndị a na-ejikarị eme ihe na mkpụrụ ndụ ihe omimi bụ mgbochi mgbochi, nke na-egbutu DNA na usoro ụfọdụ. Dịka ọmụmaatụ, enzyme EcoRV nke egosiri n'aka ekpe na-amata usoro 6-base 5′-GATC-3′ ma na-eme ka ọkpụkpụ na-agafe agafe. Na okike, enzymes ndị a na-echebe nje bacteria site na ịmịnye DNA phage mgbe ọ na-abanye na mkpụrụ ndụ bacteria, dịka akụkụ nke usoro mgbochi. Na teknụzụ, a na-eji usoro nucleases ndị a akọwapụtara na DNA molecular na cloning na mkpịsị aka mkpịsị aka
enzymes