Mezue ahịrịokwu na-esonụ: Ọnwụ Manuel na September 24, 1180, bụ ihe gbanwere ọdịnihu nke Alaeze Ukwu Byzantium. Mgbe Manuel nwụrụ, nwa ya nwoke na-eto eto bụ́ Alexios nke Abụọ Komnenos, bụ́ onye nọ n'okpuru nlekọta nke eze nwanyị Maria, nọchiri ya. Omume ya kpaliri iwe ndị mmadụ, na ọgba aghara ndị na-eso ya, nke fọrọ nke nta ka ọ bụrụ agha obodo, nyere ohere maka ọchịchọ nke nwa nwanne nna Manuel, Andronikos I Komnenos (r. 1183<unk>1185), nwa Isaac Komnenos. Andronikos hapụrụ ezumike nká ya na 1182, wee gaa Constantinople na ndị agha nke (dịka isi mmalite ndị na-abụghị Byzantine) gụnyere ndị Alakụba. N'oge na-adịghị anya, otu ìgwè ndị ozi ala ọzọ bịara.
ogbugbu nke ndị bi na Latin, nke lekwasịrị anya na ndị ahịa Venetian bụ ndị biri n'ọnụ ọgụgụ ụfọdụ na Constantinople. Ekwenyere na ọ haziri nsị nke nwanne nwanyị nke Alexius nke Abụọ bụ Maria Porphyrogenita na di ya Renier nke Montferrat, ọ bụ ezie na Maria n'onwe ya gbara ya ume itinye aka. E kwuru na ọ bụ onye ọnaozi bụ́ Pterygeonites mere nsí ahụ. N'oge na-adịghị anya mgbe nke ahụ gasịrị, o mere ka a tụọ eze nwanyị Maria mkpọrọ ma gbuo ya, site n'aka ndị Pterygeonites na "hetaireiarches" Constantine Tripsychos. A manyere Alexios nke Abụọ ikweta na Andronikos bụ onye ọrụ ibe ya na alaeze ukwu ahụ, mana e gburu ya; Tripsychos, Theodore Dadibrenos na Stephen Hagiochristophorites gburu ya. Andronikos, site na 1183 naanị eze ukwu, lụrụ Agnes nke France, nwatakịrị dị afọ iri na abụọ nke e kwere nkwa na mbụ na Alexios nke Abụọ. Agnes bụ nwa nwanyị nke Eze Louis nke Asaa nke France na nwunye ya nke atọ bụ́ Adèle nke Champagne. Ka ọ na-erule November 1183, Andronikos sonyeere nwa ya nwoke nke ọ mụrụ n'ụzọ iwu kwadoro bụ́ John Komnenos n'ocheeze ahụ.