Dee ihe na-esote paragraf a - Na Rio de Janeiro, Adrian meriri ihe nrite anọ. O nwetara ihe nrite mbụ ya dị ka arịlịka maka 4 × 100 mita freestyle relay n'akụkụ Caeleb Dressel, Michael Phelps, na Ryan Held. Ndị America, na Dressel na Held dị ka ndị asọmpi Olimpik nke mbụ, kwụsịrị na oge 3:09.92, nke France na Australia sochiri. Oge ikpeazụ Adrian gbara bụ sekọnd 46.97, nke kachasị ọsọ n'ọhịa. N'asọmpi nke mbụ ya, 100 mita freestyle
, Adrian enweghị ike ịgbachitere aha Olimpik ya, na-emetụ nke atọ n'azụ Kyle Chalmers na Pieter Timmers na 47.85 sekọnd. Adrian nwetakwara ọla nchara ọzọ n'ọsọ mita 50 n'ụdị ịgba ọsọ n'efu, na-agba ọsọ n'ihe dị ka sekọnd 21.49. Onye America ọzọ, Anthony Ervin, meriri na 21.40 sekọnd ma onye na-agbachitere Olympic Florent Manadou wee bụrụ onye nke abụọ. O ji ọlaedo ọzọ merie asọmpi Olimpik ya n'ọsọ 4x100-meter medley relay n'ụbọchị ikpeazụ nke asọmpi ahụ, na-egwu mmiri n'akụkụ Ryan Murphy, Cody Miller, na Michael Phelps. O ji 46.74 kewaa oge ya wee nweta ọla edo n'oge 3:27.95, nke bụ ihe ndekọ ọhụrụ n'egwuregwu Olimpik.