N'afọ 1893, Leon von Heppard bipụtara akwụkwọ na-akọwapụta nsonaazụ ọgwụ nke paracetamol na analgesic yana antipyretic, nke Cahn & Heppard webatara ngwa ngwa n'ọrụ ahụike n'okpuru aha nke Antifebrin site na Cahn & Heppard na 1886. Ma nsonaazụ ya na-adịghị mma na-adịghị mma <unk> nke kachasị dị egwu bụ cyanosis n'ihi methemoglobinemia <unk> kpaliri ịchọ ihe ndị na-adịghị egbu egbu nke aniline. North Harmon Morropse emeela paracetamol na Mahadum Johns Hopkins site na mbelata nke p-nitrophenol na tin na glacial acetic acid na 1877, mana ọ bụghị ruo mgbe 1887 ka onye na-ahụ maka ọgwụ na ọgwụ Joseph von Mering nwara paracetamol na ụmụ mmadụ. N'afọ 1893, Leon von Heppard bipụtara akwụkwọ na-akọwapụta nsonaazụ ahụike nke paracetamol na phenacetin, nke bụ ihe mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi
Afọ 1963