Mezue ahịrịokwu na-esonụ: Lukaku mere egwuregwu mbụ ya megide Real Madrid na 8 August na
2017 UEFA Super Cup, ma nye goolu mbụ ya maka klọb na mmeri 2-1. Egwuregwu mbụ ya n'asọmpi bịara ụbọchị ise ka e mesịrị n'ụlọ ha megide West Ham. Lukaku gbara goolu abụọ na mmeri 4 <unk> 0, wee bụrụ onye egwuregwu nke anọ nke Manchester United iji gbaa goolu abụọ na mbido Premier League ya maka klọb ahụ. N'ụbọchị iri na abụọ nke ọnwa Septemba, o nyere goolu mbụ ya na UEFA Champions League mgbe ha ji goolu atọ merie Basel. Na 17 Septemba, Lukaku gbara goolu nke atọ nke United na mmeri 4-0 na klọb mbụ ya bụ Everton, Lukaku gbara ọsọ gaa na ndị na-akwado Everton wee kpuchie ntị ya n'oge emume mgbaru ọsọ ya na nzaghachi maka ịbụ onye a na-eme mkpọtụ n'oge egwuregwu ahụ. Na 27 Septemba, Lukaku gbara goolu abụọ na mmeri 4-1 megide CSKA Moscow, na-eburu ihe mgbaru ọsọ ya ruo 10 n'ime ihe ngosi itoolu mbụ ya. Site n'ime nke a, o mebiri ihe ndekọ nke Bobby Charlton setịpụrụ bụ onye nyere goolu itoolu na egwuregwu itoolu mbụ ya maka klọb ahụ. Na mmeri 2 na 1 meriri ndị otu ya mbụ Chelsea na 25 Febụwarị 2018, Lukaku gbara goolu nha anya wee nye aka Jesse Lingard meriri egwuregwu ahụ. O nyere goolu ya nke 200 maka klọb na mba ya na 13 Machị na mmeri 2 na 1 na Sevilla nke kpochapụrụ Manchester United na Njikọ Njikọ na agba nke 16. Na 31 Machị 2018, Lukaku gbara goolu iji mepee mmeri 2-0 n'ụlọ Swansea. Ọ bụ goolu nke 100 ya na Premier League na egwuregwu nke 216 ya, ma mee ya onye nke ise nke kachasị nta n'ime ndị egwuregwu 28 iji ruo akara ahụ.