IgA1 bụ otu n'ime abụọ immunoglobulin subclasses (ndị ọzọ bụ IgD) nke na-O-glycosylated na a ọnụ ọgụgụ nke serine na threonine residues na a pụrụ iche proline-ọgaranya hinge region. Aberrant glycosylation nke IgA yiri iduga polymerisation nke IgA ụmụ irighiri na anụ ahụ, karịsịa na glomerular mesangium. A yiri usoro e ekwu na-akpata Henoch<unk>Schönpura purlein, a vasculitis na tumadi na-emetụta ụmụaka na ike Njirimara akụrụ aka na-fọrọ nke nta indistinguishable si IgA nephritis. Otú ọ dị, ụmụ mmadụ ọmụmụ hụrụ na degalactosylation nke IgA1 na-eme na eriri afọ nephropathy na-eme nanị na mpụga nke IgA na a pụrụ iche proline-ọgaranya hinge region. Nke a na-egosi na mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi mgbochi
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