Mgbe ọ malitere ọrụ ya n'elu ikpo okwu, Anderson nwetara mmata mba ụwa maka ọrụ ya dịka onye ọrụ pụrụ iche nke FBI Dana Scully na usoro ihe nkiri American sci-fi The X-Files. Ọrụ ihe nkiri ya gụnyere ihe nkiri The Mighty Celt (2005), The Last King of Scotland (2006), Shadow Dancer (2012), Viceroy's House (2017) na ihe nkiri X-Files abụọ: The X-Files: Fight the Future (1998) na The X-Files: Achọrọ m ikwere (2008). Ihe nkiri telivishọn ndị ọzọ a ma ama gụnyere: Lady Dedlock na Bleak House (2005), Wallis na Any Simpson Human Heart (2010), Miss Havisham na Great Expectations (2011), Dr. Maurilia Duer Hannibal (2013-2015), na Media Gods (2017). Na 2019, Anderson malitere igwu egwu Jean Milburn na Netflix comedy-drama Kedu Ajụjụ Mmekọahụ: Ọzụzụ?
Ihe X-Files