Mezue ahịrịokwu na-esonụ: Dị ka onye isi na-achị achị nke Low Countries, o mere Brussels, na obí Coudenberg karịsịa, dị ka ebe obibi ya na ụlọ ikpe ya: n'ebe ahụ, o kwupụtara ihe nketa ya na 1515 ma kwupụta na ọ ga-ahapụ ọchịchị na 1555. Dị ka onye na-achị Spain, o ketara ihe onwunwe nke Crown nke Aragon na ndịda Italy, ma kwado mmeri nke ndị Castillan conquistadores: Hernán Cortés jikọtara ndị Aztec ma merie Middle America na-esote
Ọdịda nke Tenochtitlan, na Francisco Pizarro meriri ndị Inca ma gbasaa ọchịchị ọchịchị na South America mgbe Agha Cajamarca gasịrị. Dị ka Emperor Rome dị nsọ o jisiri ike chebe ókèala German ya na Austria site n'aka ndị Ottoman nke Suleiman the Magnificent (Mkpọchibido Vienna) na ókèala Ịtali ya na Duchy nke Milan site na French nke Francis I (Agha nke Pavia): iji kwụọ ụgwọ Ottoman-Habsburg Wars na Italian Wars Alaeze Ukwu ahụ jiri nnukwu ọla edo na ọla ọcha na-abịa site na America. Otú ọ dị, mmụba a nke ọla ndị dị oké ọnụ ahịa mekwara ka e nwee oké onu oriri. Charles nke Ise kwadokwara ọchịchị ndị Germany na-achị Amerịka ma nye onye nchọpụta aha ya bụ Magellan ego o ji mee njem gazuo ụwa. N'ịbụ onye na-enweghị ike iguzobe ọchịchị onye eze zuru ụwa ọnụ na iguzogide ịrị elu nke okpukpe Protestant, Charles nke Ise kwupụtara na ya gaje ịgba arụkwaghịm. Nkwụsị ya kewara ókèala ya n'etiti nwa ya nwoke bụ Philip nke Abụọ nke Spain, onye weghaara ókèala ndị ọchịchị, na nwanne ya nwoke bụ Ferdinand nke Austria, Bohemia na Hungary onye weghaara Alaeze Ukwu Rom Dị Nsọ. Netherlands nke Habsburg na Duchy nke Milan nọgidere bụrụ akụkụ nke Alaeze Ukwu Rom Dị Nsọ, mana a hapụrụ ha na njikọ onwe onye na Eze nke Spain.