Mezue ahịrịokwu na-esonụ: Mgbe ọ laghachiri na United States n'etiti 1942, Wilkes gara Ụlọ Akwụkwọ Agha Agha Agha, wee bụrụ onye isi ndị isi nke ụgbọ mmiri ọhụrụ ahụ, na-ewere ya gaa Oké Osimiri Mediterenian iji sonye na mwakpo nke Sicily na July 1943. Site n'ọnwa Ọgọstụ n'afọ 1943, Rear Admiral Wilkes nwere ndị agha amphibious na England na France, na-arụ ọrụ dị mkpa na nkwadebe maka mbuso agha nke Normandy na June 1944, na
mbuso agha nke ndịda France ọnwa abụọ mgbe e mesịrị. Ka ndị Allied na-awakpo Germany, Wilkes bụ onye na-elekọta ọdụ ụgbọ mmiri na ọdụ ụgbọ mmiri US na France, na-enyere aka na mwakpo ahụ na njikwa ya.