Meester mụrụ na Fort Worth, Texas, Constance Lynn (née Haas) na Douglas Jay Meester. Nna ya bụ onye na-ere ahịa ala na ụlọ; nne ya bụ onye edemede. O nwere ụmụnne nwoke abụọ; nwanne nwoke nke okenye, Douglas Logan Meester (amụrụ 1983), na nwanne nwoke nke nta, Alexander "Lex" Meester (amụrụ 1994). N'oge a mụrụ ya, ndị nne na nna Meester nọ na-eje ozi oge n'ụlọ mkpọrọ gọọmentị etiti maka itinye aka na mgbanaka ọgwụ ọjọọ nke na-ebugharị wii wii site na Jamaica gaa United States. Constance nwere ike ịmụ Leighton n'ụlọ ọgwụ na nọọsụ ya ruo ọnwa atọ n'ụlọ ọkara, tupu ọ laghachi n'ụlọ mkpọrọ iji mezue ikpe ya. Ndị nne na nna nna ya lekọtara Meester n'oge a. O kwenyesiri ike na ndị mụrụ ya hapụrụ onye omekome, n'agbanyeghị ọnwa ha na-emebu, na nne ya bụ onye edemede.
ọnwa atọ