Rịba ama amaokwu a dị n'okpuru ma zaa ajụjụ ahụ mgbe e mesịrị n'otu asụsụ ahụ dị ka amaokwu ahụ:  Passage: Mayer na LaBruyere rụrụ na Georgia na steeti ndị dị nso. Ọzọkwa, dịka ọrụ ya dabara na ahịa egwu ịntanetị na-etolite n'oge ahụ, Mayer ritere uru site na ndị na-eso ụzọ n'ịntanetị. Mayer bịara n'anya Gregg Latterman na Aware Records site na onye maara Mayer, onye ọka iwu, onye zitere Aware EP ya. Mgbe etinyechara ya na egwu egwu Aware Festival na egwu ya na nchịkọta Aware, na mbido 2001, Aware wepụtara Mayer's album naanị ịntanetị nke akpọrọ, Room for Squares. N'oge a, Aware mechiri nkwekọrịta ya na Columbia Records nke nyere Columbia nhọrọ mbụ na ịbịanye ndị na-ese ihe Aware. N'ọnwa Septemba, Columbia weghachiri ma wepụta Room for Squares. Dị ka akụkụ nke nnukwu aha "mmalite", a na-emelite ihe osise nke album ahụ, a gbakwunyekwara egwu "3x5". Ntughari ohuru a gunyere ihe omumu ihe omumu nke ndi egwu anọ mbu site na Inside Wants Out. Ka ọ na-erule ngwụsị afọ 2002, Room for Squares emeela ọtụtụ ihe redio, gụnyere "Ọ dịghị ihe dị otú ahụ", "Okpuru gị bụ ihe ịtụnanya", na n'ikpeazụ, "Gịnị kpatara Georgia". O nwetakwara otuto n'ozuzu ya, na Mayer dọtara atụnyere Dave Matthews. N'afọ 2003, Mayer meriri Grammy maka Best Male Pop Vocal Performance maka "Your Body Is a Wonderland". N'okwu ya o kwuru mgbe ọ natara ihe nrite ahụ, o kwuru, sị, "Nke a bụ nnọọ ngwa ngwa, m na-ekwekwa nkwa na m ga-erute". O kwukwara n'ụzọ ihe atụ na ya dị afọ iri na isii, okwu nke ọtụtụ ndị weere na ọ pụtara na ọ dị afọ iri na isii n'oge ahụ. Na Febụwarị 2003, Mayer wepụtara CD na DVD nke egwu egwu na Birmingham, Alabama nke akpọrọ Any Given Thursday, nke gụnyere abụ ndị a na-edebeghị na mbụ, dịka "Man on the Side", "Something's Missing", na Covered in Rain". N'ahịa, album ahụ ruru n'ọkwa 17 na chaatị Billboard 200. E wepụtara DVD ya na-eso ya na-enweta otuto na-agbanwe agbanwe, na ndị nkatọ na-agbagha n'etiti onyinyo pop-idol ya, na (n'oge ahụ) na-apụta na guitar guitar. Erik Crawford nke AllMusic jụrụ, "Ọ bụ [Mayer] bụ dike guitar zuru oke gosipụtara mgbe ọ na-akpọ mkpuchi nke Stevie Ray Vaughan...  Ajụjụ: Olee abụ Marvin Gaye nke album ahụ wepụtara?
"Inner City Blues (Mee Ka M Chọrọ Na-eti mkpu)