N'afọ 1913, Leonor Michaelis na Maud Leonora Menten tụrụ aro ka e nwee usoro iwu nke enzyme kinetics, nke a na-akpọ Michaelis <unk> Menten kinetics. Nnukwu onyinye nke Michaelis na Menten bụ iche echiche banyere mmeghachi omume enzyme n'ụzọ abụọ. Na nke mbụ, mkpụrụ ndụ ihe nketa na-ejikọta reversibly na enzyme, na-akpụ enzyme-substrate complex. Nke a na-akpọ mgbe ụfọdụ Michaelis-Menten complex na nsọpụrụ ha. Enzyme na-emezi ihe na-akpata mmeghachi omume ahụ na usoro mmeghachi omume ahụ ma hapụ ya. A na-arụ ọrụ a site n'aka G. E. Briggs na S. B. J. Haldane, bụ ndị na-enweta data nke kinetic site na enzyme assays.
Enzymes