Ụfọdụ ndị na-akwado echiche nke memes dị ka ọdịbendị analogues ka mkpụrụ ndụ ihe nketa na ha onwe-ịmepụtaghachi, mutate, ma na-aza selective pressures. Proponents na-ekwu na memes bụ a onu na nwere ike evolve site eke selection na a n'ụzọ yiri nke ndu. Memes eme nke a site na usoro nke mutation, mmeghari, na mpi, onye ọ bụla ketara ekewa, ma ọ bụ omume, nke nwere ike na-ebute site na otu uche ọzọ site na ide, okwu, mmegharị, ememe, ma ọ bụ ndị ọzọ imitable phenomena na a mimicked isiokwu. Ụfọdụ ndị ọkà mmụta sayensị na-ekwu na nke a nwere ike ịbụ ihe ịga nke ọma site na nchọpụta na-enweghị isi nke evolushọn nke memes.
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