na-agafe agafe: Allen na-adịghị anya zigara na a undercover ozi maka CIA, isonyere Vladimir Makarov na a uka égbè na ọdụ ụgbọ elu na Moscow, Russia. Mgbe e mesịrị, Makarov egbu Allen, maara nke ya ezi njirimara, na-ahapụ ozu ya n'azụ na-akpalite a agha n'etiti Russia na United States. Outraged site a doro anya American-nkwado eyi ọha egwu agha, Russia retaliates site launching a mberede mbuso agha na East Coast nke United States. na-enweghị ihe àmà nke Makarov aka na ọdụ ụgbọ elu mgbu, Task Force 141 na-zitere Rio de Janeiro ijide ya ngwá ahịa, Alejandro Rojas. Ha na-aga nke ọma na-amụta na Makarov si nemesis na-ẹkenịmde ke Russian gulag. Ha wakpoo gulag na napụta onye mkpọrọ: Captain Price, Soap si gara aga na-enye iwu ọrụ SASPrice.
Wọshịntịn, D.C.