N'ime cytosol, ndị ọzọ na-ebugharị dopamine n'ime vesicles maka nchekwa na mgbe e mesịrị ntọhapụ. Dopamine reuptake site na DAT na-enye usoro bụ isi nke dopamine na-ekpochapụ site na synapses, ọ bụ ezie na enwere ike ịnwe ihe dị iche na prefrontal cortex, ebe ihe akaebe na-egosi na ọ nwere ike ịbụ ọrụ ka ukwuu nke onye na-ebugharị norepinephrine VN. DAT na-etinye aka na ọtụtụ nsogbu metụtara dopamine, gụnyere nkwarụ hyperactivity, nkwarụ bipolar, nkụda mmụọ, na ịṅụbiga mmanya ókè. Mkpụrụ ndụ nke na-edepụta protein mmadụ nke dị na DAT na chromosome 5, nwere 15 chromosomes, nke a na-akọwa dị ka ogologo oge.
Mkpụrụ ndụ ihe nketa nke na-ekpuchi protein DAT dị na chromosome 5 nke mmadụ, mejupụtara 15 exons na-ekpuchi, ma dị ihe dị ka 64 kbp ogologo