Rịba ama amaokwu a dị n'okpuru ma zaa ajụjụ ahụ mgbe e mesịrị n'otu asụsụ ahụ dị ka amaokwu ahụ:  N'ụzọ: De novo synthesis nke ceramide na-amalite site na mkpakọ nke palmitate na serine iji mepụta 3-keto-dihydrosphingosine. Ihe enzyme serine palmitoyl transferase na- eme ka mmeghachi omume a dị irè ma bụrụ nzọụkwụ na- egbochi ọsọ nke ụzọ ahụ. N'aka nke ya, a na-ebelata 3-keto-dihydrosphingosine ka ọ bụrụ dihydrosphingosine, nke a na-esochi acylation site na enzyme (dihydro) ceramide synthase iji mepụta dihydroceramide. A na-eme ka mmeghachi omume ikpeazụ iji mepụta ceramide site na dihydroceramide desaturase. Nchịkọta de novo nke ceramide na-eme na reticulum endoplasmic. A na-ebuzi ceramide gaa na ngwa Golgi site n'iji vesicular trafficking ma ọ bụ protein na-ebufe ceramide CERT. Ozugbo na Golgi ngwa, ceramide nwere ike n'ihu metabolized ka ndị ọzọ sphingolipids, dị ka sphingomyelin na mgbagwoju glycosphingolipids.  Ajụjụ: Gịnị na-emepụta dihydroceramide
(dihydro) ceramide synthase