 After several clashes with Wonder Woman, Queen Clea became a member of Villainy Inc., a team of super-villainesses consisting of several of Wonder Woman's Golden Age foes, including the Cheetah, Giganta and Doctor Poison.She made several Silver Age appearances (including one in "Justice League of America" #135 in 1976 in which she allied with Batman's enemies the Penguin and Blockbuster, along with the Captain Marvel foe Ibac), as well as several Post-Crisis appearances in which she was the leader of Villainy Inc.

As Queen of a crumbling Atlantean outpost named Venturia, Queen Clea enslaved the men of her realm and amused herself by putting many to death in gladiatorial combat.Wanting to extend her rule, Clea repeatedly attacked Venturia's flourishing sister city of Aurania, though unsuccessfully.