 Its headquarters was in Sydney, Australia prior to its acquisition by DXC Technology in 2011.

iSOFT was founded in 1996 as a business group within accounting group, KPMG and bought out of the Group in 1999.In 2000, iSOFT had a successful listing on the London Stock Exchange.In the summer of 2004 the "Guardian" newspaper saw a confidential report suggesting questionable accounting practices in iSOFT tracing back to 2002. iSOFT sought and obtained an injunction against the paper preventing publication of the story, and a Parliamentary Written Question was answered by the government saying that they had no plans to look into the matter.