 The drug is metabolized in the liver, mainly by 6β-hydroxylation, 5α- and 5β-reduction, 3α- and 3β-keto-oxidation, and 11β-hydroxy-oxidation.Its known active metabolites include 5α-dihydrofluoxymesterone and 11-oxofluoxymesterone.Fluoxymesterone has an elimination half-life of approximately 9.2 hours, which is long relative to that of testosterone.