 As an example, chlorotrianisene produces gynecomastia in men, albeit reportedly to a lesser extent than other estrogens, while clomifene and tamoxifen do not and can be used to treat gynecomastia.It has been reported that CTA has no measurable effect on circulating levels of testosterone in men.This is in contrast to other estrogens, like diethylstilbestrol, which can suppress testosterone levels by as much as 96%, or to an equivalent extent relative to castration.