 Josquin did not stay in Ferrara long.An outbreak of the plague in the summer of 1503 prompted the evacuation of the Duke and his family, as well as two-thirds of the citizens, and Josquin left by April of the next year, possibly also to escape the plague.His replacement, Jacob Obrecht, died of the plague in the summer of 1505, to be replaced by Antoine Brumel in 1506, who stayed until the disbanding of the chapel in 1510.