 Meanwhile, her decision to have her children inoculated after the smallpox epidemic of 1767 was responsible for changing Austrian physicians' negative view of inoculation.Maria Theresa herself inaugurated inoculation in Austria by hosting a dinner for the first sixty-five inoculated children in Schönbrunn Palace, waiting on the children herself.In 1770, she enacted a strict regulation of the sale of poisons, and apothecaries were obliged to keep a poison register recording the quantity and circumstances of every sale.