 The study was published on 29 January 2016 in the peer-reviewed "International Journal of Occupational and Environmental Health," and the Center for Science in the Public Interest downgraded sucralose from "Caution" to "Avoid".Sucralose was discovered in 1976 by scientists from Tate & Lyle, working with researchers Leslie Hough and Shashikant Phadnis at Queen Elizabeth College (now part of King's College London).While researching novel uses of sucrose and its synthetic derivatives, Phadnis was told to "test" a chlorinated sugar compound.