 After the tragedy of his family, Khả decided to abandon preparation for the priesthood and married.After his first wife died childless, Khả remarried and had twelve children with his second wife, Phạm Thị Thân (in a period of twenty-three years) of whom nine survived infancy – six sons and three daughters.These were Ngô Đình Khôi, Ngô Đình Thị Giao, Ngô Đình Thục, Ngô Đình Diệm, Ngô Đình Thị Hiệp, Ngô Đình Thị Hoàng, Ngô Đình Nhu, Ngô Đình Cẩn and Ngô Đình Luyện.