 It found that the mice on the ketogenic diet had greater kynurenic acid concentrations in the striatum and hippocampus compared to mice on a normal diet, with no significant difference in the cortex.In response to the studies showing detrimental behaviour following increases in kynurenic acid the authors also note that the diet was generally well tolerated by the animals, with no "gross behavioural abnormalities".They posit that the increases in concentrations found were insufficient to produce behavioural changes seen in those studies.