 Infected vampires can, in some cases, take centuries to die from it, growing ever weaker and more ostracized as they do.Bubonic Plague - As seen in the Jake Cutter trilogy, and in Necroscope the Lost Years, bubonic plague is also known to be lethal to vampires, though slower than how it progresses in humans.Other possible infections - It is possible, though unconfirmed, that other diseases could infect a vampire.