 The cycad hypothesis was abandoned the second time because the acute toxicity showed by Spencer and Nunn was due to BMAA concentrations in orders of magnitude higher.Further laboratory analysis which included protein-bound BMAA found significant levels in fadang, and found also that the levels were higher in fadang made at settlements with a higher incidence of lytico-bodig.The theory was resurrected by Paul Alan Cox and Oliver Sacks after re-examining aspects of the Chamorro diet.