 This nucleus has been shown to affect the release of GnRH (gonadotropin-releasing hormone) in several ways.One way is its expression of neuropeptide Y, which has an impact on the hypothalamic pathway responsible for GnRH secretion.The periventricular nucleus has also been shown to have many neurons that express kisspeptin, which generates a surge in LH, which ultimately leads to the release of GnRH.