 At twenty, he enrolled in the College of Physicians and Surgeons at Columbia University (then Columbia College), completing his medical training in 1871.Trudeau married Miss Lottie Beare in June 1871, and after a honeymoon in Europe the couple settled on Long Island NY, where Trudeau began his medical practice.Trudeau mentioned Lottie with great affection in his autobiography and remarked on the fortitude with which she met the many adversities of their married life, which included his long struggle with tuberculosis, and the deaths of three of their four children.