 During the next two and a half years, interrupted by overhaul August to December 1948, "Mattaponi" completed two round-the-world voyages in addition to making numerous runs to the Persian Gulf and one to Aruba from such ports as Yokosuka, Sasebo, Buckner Bay, Manila, Piraeus, Taranto, and Norfolk.On 21 October 1949, she entered the San Francisco Naval Shipyard for inactivation.In December she proceeded to San Diego, was immediately placed in the Reserve Fleet, and later decommissioned on 17 April 1950.