 In April 2017, biomedical manufacturing was the second largest contributor to total manufacturing value-add at 19.6 per cent.Fusionopolis One was launched on 17 October 2008, adding a second R&D hub on physical sciences and engineering.The opening of Fusionopolis came as Singapore recorded its highest Gross Domestic Expenditure in R&D (GERD) of S$6.3 billion at that time in 2007.