 MD 424 is a part of the National Highway System as a principal arterial from MD 450 north to MD 3 in Crofton.MD 424 was constructed as a wide gravel highway from what was then MD 254 (now MD 214) in Davidsonville north to US 50 (now MD 450) in 1929 and 1930.By 1934, the Maryland State Roads Commission recommended the highway be expanded to a width of for its whole length.