 Between 1570 and 1575, massive reclamation and plumbing works were undertaken on the Crostolo Stream to transport water from the streams of the mountains and from another river in the north.In 1630, a serious outbreak of plague, described in the Italian's Alessandro Manzoni's "The Betrothed", struck many parts of northern Italy.Cadelbosco was not spared, and 60 people fell victim and perished.