 It was easy and economical to reload and was once a favorite with farmers, ranchers, pot hunters, and trappers.Though the .25-20 has been used on deer and even claimed the James Jordan Buck, a whitetail deer of long standing record in 1914, it is now rarely used on large-bodied game due to its sedate ballistics and light bullet construction, which make humane one-shot kills unlikely.The .25-20 Winchester is sometimes confused with the similarly named .25-20 Single Shot; the two cartridges are markedly different and do not interchange with one another.