 Griffin's first full-length play, "Flesh and Blood", which deals with racism in Welsh society, debuted at the Sherman Theatre in Cardiff in 2000, and later moved to the Hampstead Theatre in London.In 2002, Teatr y Byd in Newport debuted another play by Griffin, "I Love You Superstar".Griffin adapted her script for "Flesh and Blood" into the screenplay for "Little White Lies", which was filmed on location in Cardiff and Swansea and premiered in the UK on 10 January 2006.