 Since there are many entropically viable forms of the molecule, it does not denature easily, and has been shown to be resistant to boiling and strong acids.α-neurotoxins antagonistically bind irreversibly to nAChRs of skeletal muscles, thereby blocking the action of ACh at the postsynaptic membrane, inhibiting ion flow and leading to paralysis.nAChRs contain two binding sites for snake venom neurotoxins.