 Defensive coordinator Bob Sanders named Williams the third cornerback on the depth chart to start the 2008 regular season, behind veterans Al Harris and Charles Woodson.In Week 4, Williams earned his first start of the season after Al Harris sustained a spleen injury the previous week.He recorded two combined tackles, broke up two passes, and intercepted a pass by quarterback Brian Griese during a 30–21 loss at the Tampa Bay Buccaneers.