 She had serious mental health issues, including bipolar disorder and agoraphobia, that ended her career as an actress and left her almost entirely homebound.Prior to her death, Marquez made headlines related to the #MeToo movement, alleging that she endured harassment while on the set of "ER".In October 2017, she accused series star George Clooney of helping to "blacklist" her after she complained to executives about the harassment.