 Escherichia coli and Salmonella are among the most important significant zoonotic pathogens causing foodborne diseases.Today, zoonosis is among the most important public health and veterinary diseases which threat human and animal life.Due to spread of new emerging diseases which made huge problems for all world health organizations, and need a specific research center, Research Institute for Zoonotic Diseases (RIZD) was first established in Iran in October 2008.