 It limits with the Paraná River in the east; and from there (going clockwise) with the departments of San Jerónimo (south), Las Colonias (west), San Justo (north) and Garay (northeast).The department has about 490,000 inhabitants, making it the second most populated in the province after the Rosario Department.Its head town is Santa Fe, which is also the provincial capital (population 370,000).