 In 1818, George partnered with his younger brother John in starting the firm of Brown Bros. & Co. in Philadelphia, Pennsylvania.His youngest brother James opened an affiliate in New York City in 1825 under the name Brown Brothers, and another in Boston in 1845.These firms were later merged under the name Brown Bros. & Co. and James's son, John Crosby Brown became a driving force for growth, making Wall Street in New York the center for operations and seeing the bank become major lenders to the textile, commodities, and transportation industries.