 The ISA has conducted a number of experiments, both manned and unmanned, in collaboration with NASA using the space shuttle.In October 1996, NASA and ISA signed an agreement for joint cooperation in the peaceful use of space - an agreement designed to develop cooperative programs of mutual interest between the two nations.The Israeli Space Agency Investigation About Hornets (ISAIAH) was project form Tel Aviv University that was initiated in the early 1990s to explorer the effects of near-zero gravity on oriental hornets, their physical and physiological development and their nest-building instincts.