 Fertilization of the egg causes a rotation of the outer cortical layers, moving clusters of the "Frizzled" and "Dsh" proteins closer to the equatorial region.β-catenin will be enriched locally under the influence of Wnt signaling pathway in the cells that inherit this portion of the cytoplasm.It will eventually translocate to the nucleus to bind TCF3 in order to activate several genes that induce dorsal cell characteristics.