 His work focussed on cardiac, respiratory, vascular and joint diseases, and emphasised postmortem examination.His fame chiefly rests on his ‘Treatise on Rheumatic Gout, or Chronic Rheumatic Arthritis of all the Joints’ (8vo, London, 1857, with an Atlas of Illustrations in 4to; 2nd edition, 1873).This work, though describing a disease more or less known for centuries, contains so much novel and important research as to have become the classical work on the subject.