 After spending Christmas Day in Santo Domingo, Heredia sailed across the Caribbean Sea to the mainland of South America where he cruised off the coast into Santa Marta Bay and then past the mouth of the Magdalena River.He passed several villages of the Mokaná Indians, until on January 14, 1533 he reached Calamari, the largest of them, standing on the sandy inner shore of Cartagena Bay.After fierce combat with the natives of the territory of Turbaco, Heredia founded a city, now Cartagena de Indias, naming it after Cartagena, Spain because it had a similar bay, but he called it "Cartagena de Poniente" to distinguish it from that city.