 Paolini was born in Milan.Seasons 2006–2007 and 2008–2010 Luca Paolini spent in two Italian cycling team – and respectively.As their member, he triumphed at certain stages of Vuelta a España and Three Days of De Panne, won one-day races Gran Premio Città di Camaiore, Trofeo Laigueglia, Coppa Placci as well as Coppa Bernocchi.