 He graduated from the law department of Columbian College (now The George Washington University Law School), Washington, D.C., in 1896, was admitted to the bar in 1897, and practiced in Baltimore, Maryland.In 1900, he married Haddie D. Gorman (who died in 1923).Gambrill served as a member of the Maryland House of Delegates from 1920 to 1922, and served in the Maryland State Senate in 1924.