 Spanoulis led the Greek national team in scoring during the 2006 FIBA World Cup, with an average of 11.7 points per game, and he also led the Greek team in free throw shooting percentage at 87.8 percent.Spanoulis also played with Greece at the 2010 FIBA World Cup, where he averaged 13.7 points per game.Fans have dubbed him V-Span and Kill Bill.