 The Latrobe River rises below Dick Hill, from the southern slopes of the Baw Baw plateau, part of the Great Dividing Range, between Powelltown and Noojee where it shares a watershed with the Little Yarra River, in a state forestry area.The river flows generally in an easterly direction, then south, and then east again through the Latrobe Valley, joined by seventeen tributaries including the Ada, Toorongo, Loch, Tanjil, Morwell, Tyers, and Thomson rivers, before reaching its mouth in Lake Wellington east of where it forms its confluence with the Avon.It then goes to flow out of Lake Wellington and into Lake Victoria, Within Lake Victoria, south of , the river forms its confluence with the Forge Creek and Mitchell River and empties into Bass Strait southwest of in the Shire of East Gippsland.