 The first NC 50 was an original state highway that ran from the South Carolina state line north through Rockingham, Aberdeen, Southern Pines, Sanford, Raleigh, Wake Forest, Henderson, Warrenton and finally Roanoke Rapids, ending at NC 4] (Weldon Road).In 1923, the section between Norlina and Roanoke Rapids was renumbered to NC 48; NC 50 was then rerouted north to Virginia.In 1925, NC 50 replaced part of NC 204 at Marston.