 Spanoulis was also selected to the EuroLeague 2005–06 season's All-EuroLeague Second Team.In 28.8 minutes per game of play, during the 2005–06 EuroLeague competition, Spanoulis averaged 14.6 points, 3.1 assists, 2.0 rebounds, and 1.4 steals, in 23 games of EuroLeague play, with Panathinaikos Athens for the season.He also shot 61.8% in 2-point shooting, and 36.8% from 3-point range; 53.4% overall.