 He established missions in Juneau and Sitka, and also founded a school and hospital in Juneau.In 1886, with two Jesuit priests, Pascal Tosi and Aloysius Robaut, and one layman, Frank Fuller, he sailed from Victoria with the intention of reaching the upper Yukon.When they reached the confluence of the Yukon River and Stewart River, Seghers decided the other two priests should spend the winter there, while he and Fuller would press on to Nulato.