 At the 2015 EuroBasket, Spanoulis led the Greek team, which had four players on it who had spent the 2014–15 season in the NBA (Giannis Antetokounmpo, Kosta Koufos, Nick Calathes, and Kostas Papanikolaou) in points per game and assists per game.Greece was ultimately defeated in the quarterfinals by Spain, by a score of 73–71, and finished the tournament in 5th place.After the tournament, Spanoulis announced his retirement from the Greek senior national team.