 A cytoskeletal example includes structures such as actin filament networks and bundles that can form from a variety of actin binding proteins that cross-link or bundle actin filaments leading to common mechanical changes of these structures.A cell machinery example includes common structures such as contractile ring formation formed by both actin and tubulin type structures leading to the same mechanical result of cell division.In order to respond to loading cells require a functional mechanome, defined as the cellular and extracellular mechanosensitive elements (genomic, proteomic, metabolic etc.)