 He developed macroporous 3D sensor arrays and synthetic tissue scaffold to mimic the structure of natural tissue, and for the first time generated synthetic tissues that can be innervated in 3D, showing that it is possible to produce interpenetrating 3D electronic-neural networks following cell culture.Lieber's current work focuses on integrating electronics in a minimally/non-invasive manner within the central nervous system.Most recently, he has demonstrated that this macroporous electronics can be injected by syringe to position devices in a chosen region of the brain.