 Originally, the S10 ran from Oranienburg to Schönefeld International Airport when line numbering was introduced to former East Berlin lines in June 1991.With the re-construction of the direct line between Frohnau and Oranienburg for the S1, the S10 terminated at Birkenwerder from May 1992.The line was redirected to Spindlersfeld from Schönefeld International Airport in May 1993, which remained the routing until the line was withdrawn in December 1999.