 A second word following the name of the antibody indicates that another substance is attached, which is done for several reasons.Emil von Behring and Kitasato Shibasaburō discovered in 1890 that diphtheria and tetanus toxins were neutralized in the bloodstream of animals by substances they called "antitoxins", which were specific for the respective toxin.Behring received the first Nobel Prize in Physiology or Medicine for their find in 1901.