 Heat-inactivated SeV virus induces the production of IL-10 and IL-6 cytokines by dendritic cells (DC).Most likely, F protein is responsible for this induction because reconstituted liposomes containing F protein can stimulate IL-6 production by DC.The production of IL-6 in response to SeV infection is restricted to conventional dendritic cells (DCs) subsets, such as CD4+ and double negative (dnDC).