 For example, the presence of Sialyl-Lewisx antigen (cluster of differentiation 15s (CD15s)), which is one of SeV cell entry receptors, on the outer cell membrane, correlates with invasion potential of malignant cells, tumor recurrence, and overall patient survival for an extremely wide range of cancers.Therefore, SeV virus preferentially can enter such cells.Expression of the Vim2 antigen , which is another SeV cell entry receptor, is very important for the extravascular infiltration process of acute myeloid leukemia cells.