 Despite missing the entire 1991 season with an injury, he rose through the Montreal farm system and made his MLB debut with the Expos on July 9, 1992, and singled in his first at bat off Francisco Oliveras of the San Francisco Giants.After his debut with Montreal, Colbrunn would also play for the Florida Marlins, Minnesota Twins, Colorado Rockies, Atlanta Braves, Arizona Diamondbacks and Seattle Mariners.He batted over .300 five times during his Major League career, and had his most successful seasons with the Marlins and Diamondbacks, exceeding the 100-games played mark in , and .