 Interferon response system is broken in these cells and it cannot protect them from SeV infection.In Namalwa cells SeV virus stimulates an expression of many genes involved in immune defense pathways, such as type I and type II IFN signaling, as well as cytokine signaling.Among the ten most virus-induced mRNAs are IFNα8, IFNα13, IFNβ, IFNλ