 Steroid sulfates like DHEA sulfate and estrone sulfate serve as large biologically inert reservoirs for conversion into androgens and estrogens, respectively, and hence are of significance for androgen- and estrogen-dependent conditions like prostate cancer, breast cancer, endometriosis, and others.Inhibitors of STS include irosustat, estrone sulfamate (EMATE), estradiol sulfamate (E2MATE), and danazol.Steryl-sulfatase is also known as "arylsulfatase", "steroid sulfatase", "sterol sulfatase", "dehydroepiandrosterone sulfate sulfatase", "arylsulfatase C", "steroid 3-sulfatase", "steroid sulfate sulfohydrolase", "dehydroepiandrosterone sulfatase", "pregnenolone sulfatase", "phenolic steroid sulfatase", "3-beta-hydroxysteroid sulfate sulfatase", as well as by its systematic name "steryl-sulfate sulfohydrolase".