 Guazzini was born at Roquebrune-Cap-Martin, Alpes-Maritimes, into a family of Italian origin (he also has an Italian passport).In 1982, he was the founder of a successful private music radio station called NRJ, until he abandoned his seat as board member in 2004.Guazzini aspired to bring back top-class rugby to the city of Paris, and in 1992 he took over Stade Français, who had been playing in the lower divisions of competition.