 The nickname of the club is "lupi" (Italian for "wolves") after the official and historical club logo, and they play their home matches at Stadio Nuovo Romagnoli.The first football club in Campobasso was founded in 1919 under the denomination of "Società Sportiva Campobasso", and achieved their first promotion to Serie C in 1975.After three seasons in Serie C, Campobasso were admitted to Serie C1 following the league split into two different tiers (Serie C1 and Serie C2); they played Serie C1 until 1981–82, when Campobasso, thanks to a second place in the final league table, achieved a historical first promotion to Serie B.

Campobasso played at the Serie B level for five consecutive seasons, the best result being in 1983–84 (seventh place); they also enjoyed a surprising 1–0 home win to Juventus in a Coppa Italia match on 13 February 1985.