 In 1384, it became a possession of the Caetani family of Fondi, but, in 1497, King Frederick IV of Naples gave the county of Fondi with the surrounding duchies, including Campodimele, to the Colonna family.In 1534, Giulia Gonzaga fled here from the Algerian pirate Hayreddin Barbarossa.In 1591, the fief was inherited by Luigi Carafa, Prince of Stigliano.