 IgA-mediated immunobullous diseases can often be difficult to treat even with usually effective medications such as rituximab.Bullous pemphigoid is a rare and chronic autoimmune disorder characterised by large sub-epidermal blisters called bullae, that predominantly involves the skin and less commonly the mucous membranes.It is the most common type of the pemphigoid group, representing 80% of sub-epidermal immunobullous cases.