 WIS 22 merges onto US 10 east (also carrying WIS 49 south and WIS 54 east) for one and a half miles, forming a brief wrong-way concurrency with WIS 49.Along with WIS 54, WIS 22 turns off US 10 to the north and into the city via Churchill Street.The two highways then turn east onto Royalton Street southeast of the city center and follow the Little Wolf River's south branch northeast.