 The institute has been used in Qajar period as a treatment center for horses, horsemen, couriers and livestock.After the First World War, due to the Treaty of Turkmenchay, the deprived Qajar state suffered from famine and widespread infectious diseases in people and livestock.It became an animal and a cold in Iran ", which was later renamed" Razi Refrigeration Company "by the order of Reza Shah Kabir and then renamed to" Razi Vaccine and Serum Research Institute ".