 Tetracycline antibiotics are often used in combination of nicotinamide to treat bullous pemphigoid.For the administration of drugs, tetracycline is prescribed as 500 mg four times daily, doxycycline and minocycline as 100 mg twice daily and nicotinamide, 500 mg 4 times daily.Dapsone is also shown to be effective in treating bullous pemphigoid.