 Thorne was born in Boston, Massachusetts of Armenian and English descent.She studied theater and dramatic literature at Wheaton College in Norton, Massachusetts and at the Lee Strasberg Theatre and Film Institute in New York City.In addition to "Rescue Me", Thorne has made guest appearances on television series such as "ER" (2005–2006), "" (, (2004), "" (2003–2019), "The Wire" (2002–2008), "Prison Break" (2006), "Royal Pains" (2009), ""White Collar"" (2009), "Burn Notice" (2009–2010), ""Californication"" (2011), and "Elementary" (2012) among others.