 He has signed with A.C. Sambonifacese on 16 July 2011 and has played 11 games in the season 2011–12.In the season 2012–13 he played for Agropoli, newly promoted in Serie D.

In 2006, Manfredini was handed his maiden national team callup by his country of birth, Ivory Coast.On 1 March 2006, Manfredini was selected for the squad to face Spain in a friendly match, however remained an unused substitute.