 The stretch of Iowa 64 between US 61 and Main Street in Maquoketa is a part of US 61 Business.At the eastern city limits of Maquoketa, Iowa 64 intersects with Iowa 62 which heads north-northeast from Maquoketa towards Bellevue.After Maquoketa, Iowa 64 continues east through rolling farmland before descending into the Goose Lake Channel and intersects CR Z20, formerly Iowa 113, near Spragueville.