 The palace dates from the early 13th-century, and takes its name from the Venetian da Mosto family, the most famous of whom was Alvise Cadamosto, an Italian explorer who worked with slave traders in Portugal, and who was born in the palace in 1432.It stayed in the da Mosto family until 1603, when Chiara da Mosto left her entire estate to Leonardo Donà dalle Rose of the Donà family, a nephew of her second husband, rather than to her da Mosto relatives, with whom she had fallen out.Between the 16th and the 18th centuries the Ca' da Mosto housed the well-known "Albergo Leon Bianco" (the White Lion Hotel).