 In a rat study at Brown Medical School, intracerebroventricular injections of the purified P57 demonstrated that the compound has a likely central nervous system (CNS) mechanism of action like that of neuroactive steroids.The studies demonstrated that the compound increases the content of ATP by 50-150% in hypothalamic neurons.In addition, third ventricle administration of P57 reduced subsequent 24-hour food intake by 40-60%.