 He made his debut for the Rangers on September 29, 2010 against Seattle, coming back from injury to throw a scoreless inning against his former team.Lowe was included on the Rangers postseason roster for 2011 after posting an ERA of 3.80 in 52 games.He was on the mound when David Freese hit the walk off home run to end Game 6 of the 2011 World Series.