 Thus, gonorrhea means "flow of seed", a description referring to the white penile discharge, assumed to be semen, seen in male infection.In 1878, Albert Neisser isolated and visualized "N. gonorrhoeae" diplococci in samples of pus from 35 men and women with the classic symptoms of genitourinary infection with gonorrhea – two of whom also had infections of the eyes.In 1882, Leistikow and Loeffler were able to grow the organism in culture.