 Convinced of its medical value, Caroline had her children Amelia, Caroline and Frederick inoculated against smallpox in the same manner.In praising her support for smallpox inoculation, Voltaire wrote of her, "I must say that despite all her titles and crowns, this princess was born to encourage the arts and the well-being of mankind; even on the throne she is a benevolent philosopher; and she has never lost an opportunity to learn or to manifest her generosity.