 This sequencing is significant due to "T. pallidum" not being capable of growing in a pure culture, meaning that this sequencing played an important role in understanding the microbe's functions.It revealed that "T. pallidum" relies on its host for many molecules provided by biosynthetic pathways, as well as it is missing genes responsible for encoding key enzymes in oxidative phosphorylation and the tricarboxylic acid cycle.It was found that this is due to 5% of "T. pallidum"'s genes code for transport genes.