 The film centers on Manuela, an Argentine nurse who oversees donor organ transplants in Ramón y Cajal Hospital in Madrid and single mother to Esteban, a teenager who wants to be a writer.On his seventeenth birthday, Esteban is hit by a car and killed while chasing after actress Huma Rojo for her autograph following a performance of "A Streetcar Named Desire", in which she portrays Blanche DuBois.Manuela has to agree with her colleagues at work that her son's heart be transplanted to a man in A Coruña.