 Paul IV had some hundred of the Marranos of Ancona thrown into prison; 50 were sentenced by the tribunal of the Inquisition and 25 of these were burned at the stake.Paul IV may be considered the instigator of one of the most wretched periods in the history of the Jews in Italy – the period of the ghettos, which dragged on for three centuries.Gian Pietro Carafa was born in Capriglia Irpina, near Avellino, into a prominent noble family of Naples.