 Penicillin can inhibit "T. pallidum" in 6–8 hours though the cells still remain in lymph nodes and regenerate.Though penicillin is not the only drug that can be used to inhibit "T. pallidum", it has also been found that any β-lactam antibiotics or macrolides can also be used.The "T. pallidum" strain 14 has built resistance to some macrolides, including erythromycin and azithromycin.