 Then in 1883, Max Bockhart proved conclusively that the bacterium isolated by Albert Neisser was the causative agent of the disease known as gonorrhea by inoculating the penis of a healthy man with the bacteria.The man developed the classic symptoms of gonorrhea days after, satisfying the last of Koch's postulates.Until this point, researchers debated whether syphilis and gonorrhea were manifestations of the same disease or two distinct entities.