 SR 372 begins at an intersection with SR 140, locally known as Arnold Mill Road, in Crabapple area of western Alpharetta, a predominately residential area of north Fulton County.After initially heading east, the route turns directly north, changes names from Crabapple Road to Birmingham Highway (named after the small community the route travels through on its way north out of Alpharetta), and heads into the western portions of Milton.SR 372 then angles slightly northeast, and briefly changes names to Birmingham Road as it crosses into Cherokee County, before making a sharp turn to the north and traveling through the unincorporated communities of Free Home and Lathemtown, now locally known as Ball Ground Road.