 On 27 August 2015, free agent Llorente signed a three-year contract with Sevilla with a buyout clause of €20 million.He made his league debut three days later, playing the full 90 minutes in a 0–3 home defeat against Atlético Madrid.He scored his first goal for the club in a 1–2 loss to Celta, also at the Ramón Sánchez Pizjuán Stadium, on 20 September.