 However, research on sustained traction of connective tissue in approaches such as adaptive yoga has demonstrated that contracture can be reduced, at the same time that tendency toward spasticity is addressed.Contractures can also be due to ischemia (restriction of blood flow) leading to death of muscle tissue, as in Volkmann's contracture.They can also be caused by excessive myofibroblast and matrix metalloproteinase accumulation in wound margins following injury.