 WIS 13 passes through Butternut and Glidden upon entering the county.Two miles northwest of Glidden, the highway joins with WIS 77 north and the two highways head north, passing through Cayuga and split with WIS 77 heading east at Mellen and WIS 13 heading northwest, passing through Highbridge, Minersville and Marengo.WIS 13 then heads north to Ashland and joins US 2 west for two miles (3 km) and then turns north (as US 2 continues west) along the Lake Superior shoreline in Bayfield County

WIS 13 closely follows the shore of Chequamegon Bay and passes through Barksdale, Washburn and Bayfield.