 On Friday 2 June 2000 the Police lay siege to his official residence in an operation to seize the Senate Mace from him but failed.Later on in 2000, he was falsely charged for corruption and impeached, officially demoting him from Senate President to a senator.In 2002 Okadigbo decamped to the All Nigeria Peoples Party to become Muhammadu Buhari's running mate in the 2003 Presidential elections, but lost to the People's Democratic Party's candidate, Olusẹgun Ọbasanjọ and his running mate, Atiku Abubakar by a landslide victory.