 Guepe played quarterback at Marquette University from 1934 to 1936 in a backfield that included two-time All-American Ray Buivid, Ray Sonnenberg, and Arthur's twin brother, Albert Guepe.The Golden Avalanche compiled records of 7–1 in 1935 and 7–2 in 1936, the latter season concluding with a 16–6 loss to Sammy Baugh and TCU in the 1937 Cotton Bowl Classic.Guepe and his twin brother, Al, starred for Marquette from 1933 to 1936.