 Flavones have no proven physiological effects in the human body and no antioxidant food value.Following ingestion and metabolism, flavones, other polyphenols, and their metabolites are absorbed poorly in body organs and are rapidly excreted in the urine, indicating mechanisms influencing their presumed absence of metabolic roles in the body.Flavones have effects on CYP (P450) activity  which are enzymes that metabolize most drugs in the body.