 Sheeppox virus (SPV) is the most severe of all the animal pox diseases and can result in some of the most significant economic consequences due to poor wool and leather quality.Goatpox is a similar disease of goats, caused by a virus antigenically distinct from "sheeppox virus".Sheeppox virus is approximately 150 kbp and shares 96% and 97% nucleotide identity with goatpox virus and lumpy skin disease virus, respectively.