 The mean apparent volume of distribution range is from 2.61 to 2.9 L/kg in healthy people and patients with cardiomyopathy.At steady state, the volume of distribution is 1.3 to 1.7 L/kg in healthy subjects, 1.3 to 1.58 L/kg in patients with coronary artery disease, and 1.25 L/kg in patients with ventricular arrhythmias receiving acecainide therapy.Acecainide has a volume of distribution of 1.5 L/kg that is less than the Vd of procinamide (2.0 L/kg).