 Although he had a very brief career as a Jesuit novice (1671–73), Domenico was never ordained a priest; he married sometime after 1686 and had three children.He is frequently confused in older scholarship with his eldest brother, Monsignor Pietro Filippo who became a prelate and canon of Santa Maria Maggiore in Rome.He devoted himself to the study of ecclesiastical history and wrote an extensive history of Catholic heresies.