 However, management of all wild melons is similar, apart from some variation in sensitivity to the herbicide glyphosate.Mechanical removal of small infestations is the simplest control method, and cultivation at early stages of growth can be effective.Large infestations are sometimes controlled by the spray-graze method, in which plants are sprayed with a sublethal dose of hormone herbicide to make them more palatable to stock, and the area is heavily grazed three days later.