 A 2016 review reported that gynephilic trans women differ from both cisgender male and female controls in non-dimorphic brain areas.Fewer studies have been performed on the brain structure of transgender men than on transgender women.A team of neuroscientists, led by Nawata in Japan, used a technique called single-photon emission computed tomography (SPECT) to compare the regional cerebral blood flow (rCBF) of 11 gynephilic FtM transsexuals with that of 9 androphilic cis females.