 Cortical thickness, which is generally thicker in cisgender women's brains than in cisgender men's brains, may also be thicker in trans women's brains, but is present in a different location to cisgender women's brains.For trans men, research indicates that those with early-onset gender dysphoria and who are gynephilic have brains that generally correspond to their assigned sex, but that they have their own phenotype with respect to cortical thickness, subcortical structures, and white matter microstructure, especially in the right hemisphere.Hormone use can also affect transgender people's brain structure; it can cause transgender women's brains to become closer to those of cisgender women, and morphological increments observed in the brains of trans men might be due to the anabolic effects of testosterone.