 In the following centuries, through ups and downs related to the names of several noble families, such as De Tufo, Capece, Brancaccio and Orsini, Montefredane gained increasing importance, until the plague of 1656 greatly reduced its development.Between 1650 and 1806 the land was owned by the noble family of Caracciolo, who brought it to its former splendor with the construction of the castle.The town was badly damaged by the 1980 Irpinia earthquake.