 Following Mill Landing Road through Wanchese, the road eventually becomes the western boundary for the Roanoke Island Marshes Dedicated Nature Preserve, before reaching its northern terminus at US 64.NC 345 is a two-lane road that begins at the intersection of Thicket Lump Drive/The Lane in southeastern Wanchese.At first the highway runs northeast along Mill Landing Road, paralleling the curve in the Roanoke Sound.