 The town's railway station, located on the Oleggio–Pino line, is an important border stop, especially for freight trains to the Gotthard railway.Passenger traffic is served by the line S30 of the Ticino railway network, operated by the international company TiLo, and by the regional trains to Gallarate, operated by the Lombard railway company Trenord.By the end of the 19th century, Luino was a heavily industrialised town; the textiles industry being particularly strong here, due to the many water courses which could be used to power the machinery and many textile factories were set up in the local area by Swiss industrialists.