 Maintaining the gains requires daily practice of the in-session learning which protects (perpetuates) the extinction of the old pathological patterns of behavior.Post-therapy practice for the rest of their lives holds in abeyance the ever-present danger of relapse and recurrence.A large-scale study, published in 2000 by Martin Keller MD of Brown University and others, compared the (then available) antidepressant Serzone with CBASP.