 The natural chemical farinomalein (a metabolite from entomopathogenic fungus "Paecilomyces farinosus") has shown potent and selective inhibition (0.15-5 μg/disk) against eight isolates of plant pathogenic "Phytophthora sojae".These results suggest that farinomalein might be useful as a candidate pesticide for the treatment of "Phytophthora" stem rot in soybean.