 Since its discovery there has been debate over chimeraplasty’s effectiveness.In the 6 September 1996 article of "Science", Kmiec claimed that chimeraplasty was 50% effective in human cells.This figure was later disputed by a number of universities; chimeraplasty is now considered from .4-2.4% effective at transforming fibroblasts, and 0.0002% effective in transforming yeast cells.