 Los Angeles Dr. Henry Pride (Bernie Casey) is an accomplished, wealthy, African American medical doctor working on a cure for cirrhosis of the liver along with his colleague, Dr. Billie Worth (Rosalind Cash).Desperate to create this remedy, Pride conducts unethical experiments on others and himself, which turns Pride into a white, Frankenstein-like monster with superhuman strength and invincibility, as he begins to rampage throughout Watts killing prostitutes and pimps.After not being able to test his remedy on Linda (Marie O'Henry), Pride goes into a rampage, which results in him being chased down by the police.