 This involves altering the endogenous genetic makeup or other biological systems of organisms.In 1995, an article titled “Production of Polyhydroxyalkanoates, a Family of Biodegradable Plastics and Elastomers, in Bacteria and Plants” describes the use of synthetic biology to increase the yield of polyhydroxyalkanoates (PHAs), specifically in "Arabidopsis" plants.Similarly, a study conducted in 1999 investigated how the oil seed rape plant can be genetically modified to produce PHBVs.