 From his studio in Cheapside, Uptton contributed illustrations to most of the major magazines of the day, including the "Strand Magazine", Tit-Bits, "Good Housekeeping", "John Bull" and "The Sphere".Between 1940 and 1942 Uptton was the political cartoonist of the "Daily Sketch" and "Sunday Graphic"; during the war he also worked for the Ministry of Information producing cartoons and posters.After the war he had a varied career as an illustrator and painter.