 In recognising children as a special class of patients, his book was one of the first treatises to make a distinction between childhood and adulthood.He recognised various mental diseases, listing of the "manye grevous and perilous diseases" to which children were susceptible, including "apostume of the brayne" (meningitis), colic, "terrible dreames and feare in the slepe" (nightmares) and "pissing in the bedde" (bedwetting).He counselled against unnecessary treatments for childhood diseases such as smallpox or measles ("The best and most sure helpe in this case is not to meddle with anye kynde of medicines, but to let nature work her operacion").