 Mötley Crüe's Nikki Sixx, in his book, "", claims that the song was specifically inspired by Neil.Joe Perry came up with the chorus riff, and Tyler came up with the chorus refrain.The video for "Dude (Looks Like a Lady)" features the band performing live onstage as well as random moments of characters portraying drag queens, including a cameo appearance by A&R man John Kalodner dressed up in a wedding dress at one point.