 In 2006, as he was 6=2 with 14 saves and a 1.95 ERA, he was International League Pitcher of the Week on July 2, mid-season All Star, post-season All Star, "Baseball America" Triple-A All Star, and MiLB.com Triple-A Reliev Pitcher of the Year.He has pitched IP in 302 games in the minors with 464 SO, a 31–19 W–L and a 2.58 ERA.Neshek made his MLB debut on July 7, 2006, pitched two innings and allowed just one hit.