 This season, he made 36 appearances out of the 38 Premier League games, as well six in the UEFA Champions League, and five in the cups.In the opening game of the 2018–19 season against Newcastle United, Vertonghen scored Tottenham's first goal of the season 8 minutes into the game, helping the team to a 2–1 win.However, he suffered a hamstring injury in the game against Huddersfield on 29 September, and was out for two months, returning to the starting lineup in the Champions League game against Inter Milan in late November.