 The hospitals Atrium Health manages in Charleston are organized as Roper-St. Francis Health System.This system was created in partnership with two other non-profit organizations, the Medical Society of South Carolina, one of the oldest continuously operating physician organizations in the United States and the owner of Roper Hospital, and the Bon Secours Healthcare System, which owns hospitals and medical facilities throughout the eastern United States.On February 8, 2018, Atrium Health announced plans to merge with Navicent Health based in Macon, Georgia 

Known as Atrium Health Urgent Care, it is a system of 33 urgent care centers in the Charlotte metropolitan area.