 The generation of glucose from compounds like pyruvate, lactate, glycerol, glycerate 3-phosphate and amino acids is called gluconeogenesis.Gluconeogenesis converts pyruvate to glucose-6-phosphate through a series of intermediates, many of which are shared with glycolysis.However, this pathway is not simply glycolysis run in reverse, as several steps are catalyzed by non-glycolytic enzymes.