 The LD50 for humans of morphine sulphate and other preparations is not known with certainty.One poor quality study on morphine overdoses among soldiers reported that the fatal dose was 0.78 mcg/ml in males (~71 mg for an average 90 kg adult man) and 0.98mcg/ml in females (~74 mg for an average 75 kg female).It was not specified whether the dose was oral, parenteral or IV.