 Food slows absorption, but does not affect the total AUC(AUC – area under the curve – meaning, food may slow absorption, but the total amount of the chemical will be absorbed with or without food).Half-life is generally in the 10–12 hour range, subject to differences in CYP genotypes, liver function and renal function.It is metabolized in the liver, and its inactive metabolite is excreted in the urine.