sentences:  Inhibition of this enzyme increases neuronal and synaptic GABA concentrations due to reduced metabolism and degradation of GABA.Inhibitors of the 4-aminobutyrate transaminase isoform include aminooxyacetic acid, gabaculine, phenelzine, phenylethylidenehydrazine (PEH), rosmarinic acid, valproic acid and vigabatrin.Some GABA transaminase inhibitors may be used clinically as anticonvulsants.