sentences:  Any new highway achieving the New Brunswick crossing would run from Interstate 395 in Brewer, Maine, to the Canada–United States border near Calais, with a direct link to New Brunswick Route 1—a major transportation corridor serving the Maritimes.A potential obstacle to the eastern end of such an American highway could be the presence of the Moosehorn National Wildlife Refuge, as its "Baring division's" easternmost extremities, on the American side, lie close to the International Avenue Bridge that crosses the international border between Maine and New Brunswick in the area.The more-southerly located link with Québec would travel northwest from Interstate 95 near Waterville, Maine, to the Canada–United States border at Coburn Gore, with a connection to a proposed extension of the "Canton de l'Est" extension of Quebec's Autoroute 10 eastwards from Montreal.