sentences:  It also plays a role in the WNT and phosphoinositide 3-kinase (especially PIK3CG) signaling pathways.Model organisms have been used in the study of GSK3A function.A conditional knockout mouse line, called "Gsk3atm1a(EUCOMM)Wtsi" was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.