sentences:  Following these trials, the FDA granted approval for the use of isavuconazole in patients with invasive aspergillosis and invasive mucomycoses, diseases that typically occur in immunocompromised patients.Basilea's antibiotic research efforts emphasize optimizing established drug mechanisms, such as beta-lactamase inhibition, as well as identification of molecular targets not currently being exploited in the antibiotic arena, with particular focus on novel inhibitors of bacterial cell-wall bio-synthesis and cell division.Basilea coordinates with other pharmaceutical companies and public research organizations as part of the NewDrugs4BadBugs program.