sentences:  Reduced levels of serotonin are believed to be responsible for the anorexic effects of DON and other trichothecenes.Irritation of the gastrointestinal tract may also play a role in reducing food intake, and may also partially explain the high incidence of paraesophageal stomach ulcers observed in sows during food refusal.In humans DON is extensively glucuronidated and excreted via urine.