sentences:  ODAP is an agonist of the ionotropic AMPA glutamate receptor.It is known to cause neurolathyrism in humans, a motor neuron degenerative disease characterized by degeneration of pyramidal-tract neurons in the spinal cord and in the area of the cortex controlling the legs, resulting in lower-body paralysis.There is not one direct explanation as to how ODAP causes neurolathyrism; however, there has been evidence to support a few biological effects.