sentences:  The process was first introduced at the scientific sessions of the American Heart Association in Anaheim in 2001, and the results were published in 2002.A few months later, Eduardo Marban's group from Johns Hopkins University published the first successful gene-therapeutic approach towards the generation of pacemaking activity in otherwise non-pacemaking adult cardiomyocytes using a guinea pig model.The investigators postulated latent pacemaker capability in normal heart muscle cells.