sentences:  Thus began Teimuraz's long and difficult reign (1605–1648) in conflict with the Safavids.In the mid-1610s, Shah Abbas I renewed his effort to bring Georgia more completely into the Safavid empire and subjected Kakheti to repeated invasions in 1614, 1615 and 1616.In a series of Georgian insurrections and Iranian reprisals, sixty to seventy thousand people were killed, and more than one hundred thousand Kakhetian peasants were forcibly deported into Iran.