sentences:  For example, PARP14, a mono ADP-ribosyltransferase, has been shown to affect STAT transcription factor binding.Other ADP-ribosyltransferases have been shown to modify proteins that bind mRNA, which can cause silencing of that gene transcript.Poly-ADP-ribose polymerases (PARPs) can function in DNA repair of single strand breaks as well as double strand breaks.