sentences:  His group also led the effort to sequence the first pediatric tumor genome for medulloblastoma.These studies defined the genomic landscapes of human cancers and identified alterations in a variety of genes and pathways not previously known to be involved in tumorigenesis, including the IDH1 and IDH2 genes in gliomas, and chromatin modifying genes MLL2/3 and ARID1 in medulloblastomas, neuroblastomas and other tumor types.In 2010, Velculescu and his group developed the PARE (personalized analysis of rearranged ends) technology that can help detect genomic tumor biomarkers circulating in the blood to enable the monitoring and personalized treatment of human cancer.