sentences:  PGD2, PGJ2, Δ12-PGJ2, and 15-deoxy-Δ12,14-PGJ2 activate the transcription factor, PPARγ, with 15-deoxy-Δ12,14-PGJ2 being the most potent of the four PGs.Accordingly, further studies have focused on 15-deoxy-Δ12,14-PGJ2.This PG directly binds with and activates PPARγ thereby inducing the transcription of genes containing the PPARγ response element.