sentences:  When a sequence of the purified protein and a cloned cDNA was extracted, it supported the claim that in fact betacellulin is a new ligand formed from the epidermal growth factor receptor (EGFR).As the role a EGFR, betacellulin is manifested by different form of muscles and tissues, it also has a great effect of nitrogen that is used for retinal pigment epithelial cells and vascular smooth muscle cells.While many studies attest a role for betacellulin in the differentiation of pancreatic β-cells, the last decade witnessed the association of betacellulin with many additional biological processes, ranging from reproduction to the control of neural stem cells.Betacellulin is a member of the EGF family of growth factors.