sentences:  Alexander Shulgin was likely the first to synthesize MMDA-2.In his book "PiHKAL", the dose is listed as 25–50 mg, and the duration is listed as 8–12 hours.Shulgin reports that MMDA-2 produces effects such as enhanced awareness, empathy, and visual facilitation and distortion, as well as some side effects like gastrointestinal upset and appetite loss.