sentences:  Yet cefoxitin was the compound that was successful in keeping its previous effectiveness against Gram negative bacteria, developed effectiveness against Gram positive bacteria, and was resistant to breakdown by beta-lactamase.Cefoxitin, and the cephamycin family as a whole, served as a branching point and impulsed the discovery of more classes of beta-lactams.This is in part due to their primary and early discovery in the broths studied.