sentences:  With the advent of multiplex ligation-dependent probe amplification (MLPA) technology, partial deletions of the "FLCN" gene have also been identified  permitting a "FLCN" mutation detection rate in BHD cohorts that approaches 90%.Very few "FLCN" mutations have been found in association with sporadic kidney tumors indicating that "FLCN" mutation may play only a minor role in non-inherited kidney cancer.Experimental evidence supports a role for "FLCN" as a tumor suppressor gene.