sentences:  The same abbreviation ("PNPase") is also used for another, otherwise unrelated enzyme, Purine nucleoside phosphorylase.Model organisms have been used in the study of PNPT1 function.A conditional knockout mouse line, called "Pnpt1tm1a(KOMP)Wtsi" was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.