sentences:  Refeeding of amino acids stimulated Lst4-Lst7 binding to and GAP activity towards Gtr2 resulting in mTORC1 activation and demonstrating conservation of a GAP function for FLCN in lower organisms.TFE3 and TFEB are members of the microphthalmia-associated transcription factor (MiTF) family, which also includes MiTF and TFEC.Gene fusions of "TFE3" with a number of different gene partners can arise sporadically and are responsible for Xp11.2 translocation renal cell carcinoma.