sentences:  The TLR-4-Asp299Gly point mutation is strongly correlated with an increased infection rate with "Plasmodium falciparum".It appears that the mutation prevents TLR4 from acting as vigorously against, at least some plasmodial infections.The malaria infection rate and associated morbidity are higher in TLR-4-Asp299Gly group, but mortality appears to be decreased.