sentences:  A 2016 review indicates that some immunotherapeutic strategies have shown encouraging results in early-phase clinical trials.Elevations of serum mesothelin specific to ovarian and other cancer patients may be measured using ELISA assays.Soluble mesothelin is identified as the extracellular domain of membrane-bound mesothelin shed from tumor cells according to the mass spectrometry analysis of soluble mesothelin purified from cell culture supernatant.