sentences:  Fetuin-A facilitates the binding of lipids to receptors, thereby inducing insulin resistance.TLR4 expression can be detected on many tumor cells and cell lines.TLR4 is capable of activating MAPK and NF-κB pathways, implicating possible direct role of cell-autonomous TLR4 signaling in regulation of carcinogenesis, in particular, through increased proliferation of tumor cells, apoptosis inhibition and metastasis.