sentences:  It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".ACA70 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein.snoRNA ACA70 is predicted to guide the pseudouridylation of U1692 of 18S ribosomal RNA (rRNA).