sentences:  Rhabdomyosarcoma is a highly malignant form of cancer that develops from immature skeletal muscle cell precursors viz., myoblastss that have failed to fully differentiate.FGFR1 activation causes myoblast to proliferate while inhibiting their differentiation, dual effects that may lead to the assumption of a malignant phenotype by these cells.The 10 human rhabdomyosarcoma tumor exhibited decreased levels of methylation of CpG islands upstream of the first FGFR1 exon.