sentences:  Mecasermin rinfabate was developed by INSMED corporation for the treatment of growth failure in children with severe primary IGF-I deficiency (primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH.Due to a patent settlement, Iplex is being taken off the market for short stature related indications.However, Iplex is being studied as a treatment for other several serious medical conditions.