sentences:  Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FG23 bind and activate FGFR1.FGFs binding to FGFR1 is promoted by their interaction with cell surface heparan sulfate proteoglycans and, with respect to FGF19, FGF20, and FGR23, the transmembrane protein Klotho.FGFR1, when bound to a proper FGF, elicits cellular responses by activating signaling pathways that include the