sentences:  Since most cellular processes, such as the cell cycle and cancer, involve changes in the cytoskeleton; it becomes apparent why TCTP is important.Moreover, if the gene encoding TCTP is knocked-out in mice, it becomes embryonic lethal, and they die "in utero" (in the womb).Translationally Controlled Tumor Protein (TCTP/tpt1) is a regulator of the cancer stem cell compartment, the tumor reversion program, tumor progression and certain forms of inflammatory diseases.