sentences:  The city experienced a relatively sharp increase in the number of business deaths, the largest increase of all the Core Cities, however this was offset by strong growth in new businesses which resulted in a strong net growth.Manchester is a major headquarters location, with a growing number of global, European and national headquarter offices.International property experts Cushman & Wakefield have ranked Manchester as the best city to locate a new headquarters operation largely down to ease of access to a pool of knowledge and global connectivity.