sentences:  XDR-TB was first widely publicised following the report of an outbreak in South Africa in 2006.53 patients in a rural hospital in Tugela Ferry were found to have XDR-TB of whom 52 died.The median survival from sputum specimen collection to death was only 16 days and that the majority of patients had never previously received treatment for tuberculosis suggesting that they had been newly infected by XDR-TB strains, and that resistance did not develop during treatment.