sentences:  The hope of this 2001 study was that alternating weeks of drug-taking with weeks of drug abstinence would both reduce toxicity and cost to the patients.This small, uncontrolled study found that a structured intermittent therapy (SIT) approach may help to maintain health while also reducing cost and toxicity of antiretroviral therapy.This approach might have had particular applicability in resource-poor settings where access to therapy is limited by the cost of antiretroviral agents.