sentences:  Using primarily sera from early, acute Lyme patients, Steere formulated serodiagnostic criteria for Western blotting, a technique which identifies antibodies in the serum directed against foreign antigen, in this case, "B. burgdorferi", the causative agent of Lyme disease.By the mid-1990s, Steere had watched Lyme disease gain acceptance, but he worried that Lyme disease had become a nonspecific diagnosis covering maladies ranging from chronic fatigue syndrome (CFS), fibromyalgia to hypochondria.Steere was concerned that many people with no evidence of past or present Lyme disease receiving antibiotic treatments, especially treatments beyond the recommended four week treatment guideline protocol, "were being done more harm than good".