sentences:  Because it inactivates the RNA polymerases, the liver is unable to repair the damage that beta-amanitin causes and the cells of the liver disintegrate and the liver dissolves.Due to its lethality and its widespread presence in the genus "Amanita", which is found across the globe, β-amanitin has been extensively studied in the field of protein biochemistry.In particular, William Lipscomb, Nobel laureate, greatly contributed to characterizing this protein.