sentences:  Wiley claims the protocol is a step beyond the symptomatic treatment of conventional hormone replacement therapy.The protocol has been criticized by members of the medical community for the dosages of the hormones used, side effects of the treatment, potential physiologic effects, Wiley's lack of medical or clinical qualifications to design the protocol, lack of empirical evidence demonstrating it as safe or effective, ethical problems with the clinical trial that is being run to test it and potential financial conflicts of interest regarding financial incentives.The Wiley Protocol uses bioidentical hormones, specifically estradiol and progesterone.