sentences:  JDP 2 was found by a Sos-recruitment system, to dimerize with c-Jun to repress AP-1-mediated activation.It was later identified by the yeast-two hybrid system to bind to activating transcription factor 2 (ATF2) to repress ATF-mediated transcriptional activation.JDP2 regulates 12-O-tetradecanoylphorbol-13-acetate (TPA) response element (TRE)- and cAMP-responsive element (CRE)-dependent transcription.