sentences:  All syndecans have an N-terminal signal peptide, an ectodomain, a single hydrophobic transmembrane domain, and a short C-terminal cytoplasmic domain.All syndecans are anchored to plasma membrane via a 24-25 amino acid long hydrophobic transmembrane domain, in contrast to another type of cell surface proteoglycans that attaches to cell membrane using a glycosyl-phosphatidyl-inositol linkage.The most obvious differences between syndecans include
  (together with differences in distribution) the subclassification
  of the family depending on the existence of GAG binding
  sites either at both ends of the ectodomain (syndecan-1 and -
  3) or at the distal part only (syndecan-2 and -4) and a relatively
  long Thr-Ser-Pro-rich area in the middle of syndecan-
  3’s ectodomain.