sentences:  For example, in the epithelial-derived tumor cell line, S115, the syndecan 1 ectodomain suppresses the growth of S115 cells without affecting the growth of normal epithelial cells [7].However, syndecan 1 expression also has a role in tumor progression in myeloma and other cancers [5, 6, 9, 15].It associates with intracellular actin cytoskeleton and helps maintain normal epithelium sheet morphology
  
  The syndecan proteins can contain the following protein domains,
  
  Syndecan-4 is upregulated in endometriosis and inhibition of syndecan-4 in human endometriotic cells results in a reduction of invasive growth in vitro and changes in matrix metalloproteinase expression.