sentences:  The most common translocation, present in about 90% of Ewing sarcoma cases, is t(11;22)(q24;q12), which generates an aberrant transcription factor through fusion of the "EWSR1" gene with the "FLI1" gene.The pathologic differential diagnosis is the grouping of small-blue-round-cell tumors, which includes lymphoma, alveolar rhabdomyosarcoma, and desmoplastic small round cell tumor, among others.On conventional radiographs, the most common osseous presentation is a permeative lytic lesion with periosteal reaction.