sentences:  The Harvard research group leading the study screened 16,000 compounds, looking for one that would displace a fluorescein-labeled peptide derived from the eIF4G sequence that binds to the eIF4E form at the same site.Eventually they turned up 4EGI-1, which displaced eIF4G by binding to a smaller subset of its binding site (on eIF4E).The newly found molecule had the added advantage of enhancing 4E-BP1 binding, a surprise given that this molecule is also believed to bind eIF4E via the same motif.