sentences:  The inhibition of these initiation factors prevents the initiation and translation of many proteins whose functions are essential to the rapid growth and proliferation of cancer cells.4EGI-1 mimics the action of a class of cellular regulatory molecules that naturally inhibit the binding of two initiation factors necessary for interaction of transcribed mRNA with the subunits of ribosomal complexes.These naturally occurring regulatory molecules, or binding proteins (BPs), bind to eukaryotic initiation factor eIF4E, preventing its association with eIF4G, another initiation factor.