sentences:  "Ogataea polymorpha" (synonyms "Hansenula polymorpha" or "Pichia angusta") is another methylotrophic yeast (see "Candida boidinii").It can grow on a wide range of other substrates; it is thermo-tolerant and can assimilate nitrate (see also Kluyveromyces lactis).It has been applied to the production of hepatitis B vaccines, insulin and interferon alpha-2a for the treatment of hepatitis C, as well as to a range of technical enzymes.