sentences:  Thus it came that in 1868, in turn alizarin was proved to be obtainable from anthracene, in parallel by Perkin and by Carl Gräbe and Carl Theodore Liebermann, both working in Germany for the BASF company; unfortunately Perkin missed the patent priority by one single day, alizarin's extraordinary properties made it become the first really mass industry-produced dye and enabled the rise of BASF to first rank in the chemistry industry world.Codeine is probably Robiquet's most important contribution, that prevails still today with a very strong presence and impact on daily life; in effect, until the beginning of the 19th century, raw opium was used in diverse preparations known as laudanum (see Thomas de Quincey's "Confessions of an English Opium-Eater"), paregoric elixirs (a number of them, very popular in England since the beginning of the 18th century), and health or even death hazards to users from improper preparation or improper use were frequent.The isolation of codeine by Robiquet from opium's several active components while working on refined morphine extraction processes, opened the path to the elaboration of a new generation of specific antitussive and antidiarrheal potions of much safer use, based on codeine only, which became immediately extremely popular.