sentences:  Progesterone-only type contraceptives and long-acting reversible contraception are associated with worsened acne.Antiandrogens such as cyproterone acetate and spironolactone can successfully treat acne, especially in women with signs of excessive androgen production, such as increased hairiness or skin production of sebum, or baldness.Spironolactone is an effective treatment for acne in adult women.