sentences:  However, 5α-reductase inhibitors can be combined with birth control pills to prevent pregnancy, and are frequently used to treat excessive hair in women.There is no evidence as of 2010 to support the use of cimetidine or ketoconazole in the treatment of acne.Hormonal treatments for acne such as combined birth control pills and antiandrogens may be considered a first-line therapy for acne under many circumstances, including desired contraception, known or suspected hyperandrogenism, acne during adulthood, acne that flares premenstrually, and when symptoms of significant sebum production (seborrhea) are co-present.