sentences:  Unlike combined birth control pills, it is not approved by the United States Food and Drug Administration for this purpose.Spironolactone is an aldosterone antagonist and is a useful acne treatment due to its ability to additionally block the androgen receptor at higher doses and thus reduce sebum production.Alone or in combination with a birth control pill, spironolactone has shown a 33 to 85% reduction in acne lesions in women.